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Title of Journal: Neuroradiology

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Abbravation: Neuroradiology

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Springer-Verlag

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10.1007/978-3-319-09327-7_2

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1432-1920

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Flow diverter effect on cerebral aneurysm hemodyna

Authors: Breigh N Roszelle L Fernando Gonzalez M Haithem Babiker Justin Ryan Felipe C Albuquerque David H Frakes
Publish Date: 2013/03/21
Volume: 55, Issue: 6, Pages: 751-758
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Abstract

Flow diverting devices and stents can be used to treat cerebral aneurysms too difficult to treat with coiling or craniotomy and clipping However the hemodynamic effects of these devices have not been studied in depth The objective of this study was to quantify and understand the fluid dynamic changes that occur within bifurcating aneurysms when treated with different devices and configurationsTwo physical models of bifurcating cerebral aneurysms were constructed an idealized model and a patientspecific model The models were treated with four device configurations a single lowporosity Pipeline embolization device PED and one two and three highporosity Enterprise stents deployed in a telescoping fashion Particle image velocimetry was used to measure the fluid dynamics within the aneurysms pressure was measured within the patientspecific modelThe PED resulted in the greatest reductions in fluid dynamic activity within the aneurysm for both models However a configuration of three telescoping stents reduced the fluid dynamic activity within the aneurysm similarly to the PED treatment Pressure within the patientspecific aneurysm did not show significant changes among the treatment configurations however the pressure difference across the untreated vessel side of the model was greatest with the PEDTreatment with stents and a flow diverter led to reductions in aneurysmal fluid dynamic activity for both idealized and patientspecific models While the PED resulted in the greatest flow reductions telescoping highporosity stents performed similarly and may represent a viable treatment alternative in situations where the use of a PED is not an option

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