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Title of Journal: Neuroradiology

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Abbravation: Neuroradiology

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Springer-Verlag

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10.1016/0263-2241(93)90007-5

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1432-1920

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The appearance of ADCs in the nonaffected areas o

Authors: Zhenghua Liu Xiwei Liu Lihong Hui Danhua Zhao Xiaoying Wang Sheng Xie Jiangxi Xiao Xuexiang Jiang
Publish Date: 2010/06/17
Volume: 53, Issue: 4, Pages: 227-232
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Abstract

The exact mechanism of the mitochondrial myopathy encephalopathy lactic acidosis and strokelike episodes MELAS remain unclear Diffusionweighted imaging DWI is a magnetic resonance MR imaging technique for studying the pathophysiologic change of the MELAS The purpose of the study is to see whether the apparent diffusion coefficient ADC of MELAS in the nonaffected areas is different from the ADC of the normal subjects and to speculate the pathophysiological mechanisms of the MELASSixteen cases of MELAS were retrospectively analyzed Thirty healthy subjects were chosen to constitute the control group All of them were performed on the 30T wholebody MR scanner with axial view T2 fluid attenuated inversion recovery flair T2weighted imaging T1flair and DWI An ADC map was reconstructed in the workstation Two to five regions of interest were put in the nonaffected frontal lobe and basal ganglia All data took statistical analysis

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