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Title of Journal: Indian J Pediatr

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Abbravation: The Indian Journal of Pediatrics

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Springer-Verlag

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DOI

10.1007/bf01409589

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0973-7693

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Hypophosphatasia associated with Pseudotumor cereb

Authors: Serap Teber Taner Sezer Mehpare Kafali Tanil Kendirli Zeynep Siklar Merih Berberoglu Gönül Öcal Gülhis Deda
Publish Date: 2008/06/22
Volume: 75, Issue: 2, Pages: 186-188
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Abstract

We report a 3monthold male with infantile hypophosphatasia who later developed Pseudotumor cerebri At the age of 3 months he was referred to our hospital because of pneumonia and respiratory insufficiency He had short extremities and radiographs of the bones were consistent with lack of metaphyseal mineralization and bowed lower extremities Vomiting and bulging fontanelle developed 3 months after admission and CSF openning pressure was notably high at 430 mm/H2O Hypophosphatasia is a very rare cause of pseudotumor cerebri This report is the first case where PTC is associated with hypophosphatasia and responded well to corticosteroid therapy

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