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Title of Journal: Indian J Pediatr

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Abbravation: The Indian Journal of Pediatrics

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Springer-Verlag

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DOI

10.1007/s00092-012-0525-6

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0973-7693

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Calcified Cerebral Cryptococcal Granuloma

Authors: JingQi Zhu XiaoFeng Tao WeiQun Bao NanXin Hao XiangRu Wu
Publish Date: 2012/04/28
Volume: 80, Issue: 4, Pages: 345-348
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Abstract

The authors report a 12moold girl with calcified cerebral cryptococcal granuloma She was admitted with a 6mo history of seizures Laboratory examinations showed no abnormal findings Electroencephalography revealed bilateral slow wave activity greater in the right occipital region CT showed an irregular calcified focus with small surrounding low density in the right parietooccipital region MRI demonstrated mixed signals without edema and visible flowvoids The clinical symptoms mimicked intracranial vascular malformations The diagnosis of cerebral cryptococcal granuloma was made by histopathology Partial resection of the lesion with postoperatively antifungal and anticonvulsant therapy offered the satisfactory result Cerebral cryptococcal granuloma is extremely rare especially in infants Calcification is indeed unusual Cerebral cryptococcal granuloma should be included in the differential diagnosis of intracranial mass with calcification in infants

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