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Title of Journal: Indian J Pediatr

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Abbravation: The Indian Journal of Pediatrics

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Springer-Verlag

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DOI

10.1002/chin.201527110

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0973-7693

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Erosive Potential of Sugar Free and Sugar Containi

Authors: Ruchi Arora Utsav Mukherjee Vivek Arora
Publish Date: 2011/08/10
Volume: 79, Issue: 6, Pages: 759-763
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Abstract

Overall 55 59 formulations had an endogenous pH of 55 The mean ±SD endogenous pH and titratable acidity for 45 SC formulations were 552 ± 118 and 0165 ± 0131 mmol respectively for 49 sugarsfree SF formulations these figures were 581 ± 143 and 0393 ± 1225 mmol P  005Compared with their SC bioequivalents eight SF medicines showed no significant differences for pH or titratable acidity while 10 higherstrength medicines showed lower pH P 0035 and greater titratable acidity P 0026 than their lowerstrength equivalents Chewable and dispersible tablets gastrointestinal medicines and antibiotics were significant predictors of higher pH In contrast effervescent tablets and nutrition and blood preparations were significant predictors of higher titratable acidity

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