Authors: Sevim Balci Ozlem Engiz Mehmet Alikasifoglu Ibrahim Esinler M Sinan Beksac
Publish Date: 2008/08/31
Volume: 75, Issue: 6, Pages: 638-
Abstract
Recently many reports have been published on the use of intracytoplasmic sperm injection ICSI and the increased risk of congenital major malformations or syndromes We present three cases with Goldenhar syndrome one of them a twin pair and one case with RubinsteinTaybi syndrome RTS also a twin pair All four female cases are derived from ICSI Goldenhar syndrome with ICSI pregnancy has been reported previously but as far as we know RTS has not been described in association with assisted reproductive technology ART The four new cases reported herein will contribute to a better understanding whether ICSI pregnancy increases congenital malformations
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