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Title of Journal: Indian J Pediatr

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Abbravation: The Indian Journal of Pediatrics

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Springer-Verlag

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DOI

10.1002/lipi.19120190210

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0973-7693

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Essential Thrombocytosis and Antiphospholipid Anti

Authors: Dinesh Yadav Jagdish Chandra Sunita Sharma Varinder Singh
Publish Date: 2011/08/10
Volume: 79, Issue: 4, Pages: 538-540
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Abstract

Essential thrombocytosis is extremely rare in children However when present it is associated with increased prevalence of antiphospholipid antibodies and thrombohemorrhagic complications The authors report here a child with BuddChiari Syndrome resulting from essential thrombocytosis and associated antiphospholipid antibodies A 13 yold boy presented with microcytic hypochromic anemia hepatosplenomegaly and thrombocytosis CT scan demonstrated calcified thrombus in inferior vena cava IVC Diagnosis of essential thrombocytosis was considered in view of persistent thrombocytosis antiphospholipid antibodies bone marrow showing increased number clusters and giant forms of megakaryocytes and IVC thrombosis He was started on warfarin prophylaxis and did not have thrombotic recurrence on follow up

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