Authors: Janette McDougall Miranda Tsonis
Publish Date: 2009/06/02
Volume: 17, Issue: 10, Pages: 1231-
Abstract
A review was conducted that used the databases MEDLINE PubMed PsycINFO and CINAHL Articles were included that were published in English between 2001 and 2008 and used quantitative measures and statistical tests to compare healthrelated quality of life HRQL or QOL of childhood cancer survivors with population norms or matched comparison groupsThirteen studies were identified Findings were contradictory across studies yet by and large reflected those of past reviews In general survivors’ scores on subscales representing physical psychological and social domains of HRQL/QOL were similar to comparisons with the greatest differences being in physical wellbeing Key personal and environmental factors were negatively correlated with the three domains across studies for survivors including older age at diagnosis longer time since diagnosis certain cancer and treatment types female gender and a number of socioeconomic factorsLack of comparability across studies remains a problem due to wide variation in study focus and designs Conceptual and methodological issues include use of numerous HRQOL and QOL measures lack of distinction between conceptualization and measurement of HRQL and QOL lack of initial qualitative input from survivors about QOL little examination of the influence of environmental factors on QOL little attention to survivors’ satisfaction with life quality use of small heterogeneous samples and need for populationbased longitudinal studies
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