Authors: Minsoo Kim Shin Ahn Won Young Kim Chang Hwan Sohn Dong Woo Seo YoonSeon Lee Kyung Soo Lim
Publish Date: 2017/01/06
Volume: 25, Issue: 5, Pages: 1557-1562
Abstract
In Sepsis3 the quick Sequential Organ Failure Assessment qSOFA score was developed as criteria to use for recognizing patients who may have poor outcomes This study was performed to evaluate the predictive performance of the qSOFA score as a screening tool for sepsis mortality and intensive care unit ICU admission in patients with febrile neutropenia FN We also tried to compare its performance with that of the systemic inflammatory response syndrome SIRS criteria and Multinational Association of Supportive Care in Cancer MASCC score for FNWe used a prospectively collected adult FN data registry The qSOFA and SIRS scores were calculated retrospectively using the preexisting data The primary outcome was the development of sepsis The secondary outcomes were ICU admission and 28day mortalityOf the 615 patients 100 developed sepsis 20 died and 38 were admitted to ICUs In multivariate analysis qSOFA was an independent factor predicting sepsis and ICU admission However compared to the MASCC score the area under the receiver operating curve of qSOFA was lower qSOFA showed a low sensitivity 014 02 and 023 but high specificity 098 097 and 097 in predicting sepsis 28day mortality and ICU admission
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