Authors: Mustafa Ozturk Seref Komurcu Selim Kilic Ahmet Ozet Fikret Arpaci Bekir Ozturk Okan Kuzhan Selmin Ataergin
Publish Date: 2009/02/06
Volume: 17, Issue: 10, Pages: 1295-1299
Abstract
Patients with hematologic or solid tumors who underwent conditioning regimen were asked to score mucositis severity daily from the first day to the tenth day of reinfusion Patientreported scoring was performed according to a fivegrade scale 0 no symptom 1 mild 2 moderate 3 severe 4 very severe Total mucositis score TMS was defined as the addition of daily mucositis scores for 10 days A total of 68 SCT 58 autologous and 10 allogeneic patients 48 men 71 and 20 women 29 were included to the study Median age of patients was 325 range 15–78 years The most frequent three diagnosis were nonHodgkin’s lymphoma 37 n = 25 Hodgkin’s lymphoma 12 n = 8 and multiple myeloma 12 n = 8 BEAM n = 27 ICE n = 17 melphelan 200 mg/m2 M200n = 8 and TBI+C total body irradiation + cyclophosphamide n = 16 were used as conditioning regimensAll of the patients experienced mucositis at any grade TMS in the sixth day was higher than TMS in the first day p 005 TMS was not related to the diagnosis or gender p 005 TMS at ICE regimen in the first 5 days after transplantation was more severe than BEAM regimen TMS at TBI+C regimen was higher than TMS at BEAM regimen from day 4 to day 10 p 005 The mean percentages of patients who scored severe or very severe mucositis in 10 days was 74 in BEAM 89 in ICE 125 in M200 and 312 in TBI+C groups
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