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Title of Journal: Neurol Sci

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Abbravation: Neurological Sciences

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Springer Milan

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DOI

10.1002/ana.410100622

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1590-3478

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Neuropsychological assessment in myasthenia gravis

Authors: Emilia J Sitek Małgorzata M Bilińska Dariusz Wieczorek Walenty M Nyka
Publish Date: 2009/01/16
Volume: 30, Issue: 1, Pages: 9-14
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Abstract

Neuropsychological studies in myasthenia gravis MG were undertaken to prove the central nervous involvement However they still produce contradictory results In the present study a battery of cognitive measures was administered to examine global cognitive functioning verbal learning attention executive function and motor performance Analysis of partial scores in verbal learning and response fluency trials did not reveal fatigue effect in MG patients It was shown that in tasks requiring motor and particularly oculomotor involvement the muscle fatigue could account for the deficits observed Thus impaired performance on some cognitive measures in MG should be interpreted as an effect of muscle fatigability rather than central nervous system involvement

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