Authors: Maria Grazia Passarin Patrick Y Wen Emanuela Vattemi Ebba Buffone Claudio Ghimenton Lamberto Bontempini Sarah Ottaviani Anna Maria Musso Rebecca Pedersini
Publish Date: 2010/06/02
Volume: 31, Issue: 6, Pages: 793-797
Abstract
Intravascular lymphomatosis IVL is a rare malignant B or Tcell lymphoma with remarkable affinity for the endothelial cells of small vessels particularly within the skin and central nervous system It is a disease that mimics several neurological disorders particularly those of cerebrovascular ischemic origin The prognosis is generally poor with a rapidly fatal outcome As a result the diagnosis is often made at postmortem We report a rare case of a 73yearold patient with IVL complicated by intracerebral haemorrhage In literature two cases of systemic IVL complicated by intracerebral haemorrhage have been reported but they presented initially with a disseminated intravascular coagulation DIC This is the first case of brain IVL complicated by intracerebral haemorrhage not associated to DIC Increasing awareness of this disease as a differential diagnosis to a common clinical presentation may lead to more opportunities to evaluate new diagnostic and treatment approaches
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