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Title of Journal: Neurol Sci

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Abbravation: Neurological Sciences

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Springer Milan

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DOI

10.1002/oa.1230

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1590-3478

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Prevalence of headache in patients with Parkinson’

Authors: Jean Costa Nunes E N Costa Bergamaschi F C Freitas A P Diaz L P Queiroz R Debona R D S Prediger M N Linhares K Lin Roger Walz
Publish Date: 2013/11/07
Volume: 35, Issue: 4, Pages: 595-600
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Abstract

We compared the lifetime prevalence and the prevalence of headache during the previous year in patients with Parkinson’s disease PD and control subjects We also investigated the association between the side of PD symptom onset and the side of the headache We interviewed 98 consecutive patients with an established diagnosis of PD between December 2010 and January 2012 The control group consisted of the 98 oldest sexmatched individuals from the nationwide Brazilian headache database PD patients showed a significantly lower prevalence 408  of headache in the previous year than controls 694  adjusted OR 05 CI 95  02–09 p = 003 PD patients also showed a lower prevalence of headache throughout life 745  than controls 939  adjusted OR 02 CI 95  01–06 p = 001 Considering only patients who presented headache during the previous year PD patients showed a higher association with occurrence of migraine than tensiontype headache compared with controls adjusted OR 33 CI 95  12–89 p = 002 The headache side was ipsilateral to the side of PD onset in 21 patients 84  with a concordance of 857  on the left side and 818  on the right side p  001 The prevalence of primary headache was significantly lower in patients with PD than controls The predominant side of headache was ipsilateral to the side of initial motor signs of PD

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