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Title of Journal: J Mater Sci Mater Med

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Abbravation: Journal of Materials Science: Materials in Medicine

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Springer US

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DOI

10.1007/bf01489408

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1573-4838

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Nanohydroxyapatite/polyEmphasis Type="SmallCaps

Authors: C Y Zhang H Lu Z Zhuang X P Wang Q F Fang
Publish Date: 2010/10/02
Volume: 21, Issue: 12, Pages: 3077-3083
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Abstract

Nanohydroxyapatite/polyllactic acid nanoHA/PLLA composites with uniform HA distribution and good mechanical performance were fabricated by a modified in situ precipitation method using CaOH2 and H3PO4 as precursors for the synthesis of HA phase This method has solved the aggregation problem of the nanosized particles in the polymer matrix The Xray diffraction Fourier transform infrared spectroscopy and transmission electron microscopy were used to characterize the phase composition chemical interactions and morphology of the composites while the mechanical properties were determined by compressive measurements The results show that the rodlike nanoHA particles synthesized by this method were uniformly distributed in the PLLA matrix The compressive strength and Young’s modulus of the composites were greatly enhanced and reached the values of 155 MPa and 36 GPa at 20 wt HA content respectively which are much higher than those of the reference samples fabricated by direct mixing of PLLA with nanoHA particles This supports the potential of these composites for applications in bone tissue engineering and load bearing bone defects repair


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  2. Mechanical strength of ceramic scaffolds reinforced with biopolymers is comparable to that of human bone
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  7. Poly ( d , l -lactide)/nano-hydroxyapatite composite scaffolds for bone tissue engineering and biocompatibility evaluation
  8. Bone-like apatite coating on Mg-PSZ/Al 2 O 3 composites using bioactive systems
  9. Using chondroitin sulfate to improve the viability and biosynthesis of chondrocytes encapsulated in interpenetrating network (IPN) hydrogels of agarose and poly(ethylene glycol) diacrylate
  10. The preparation, cytocompatibility, and in vitro biodegradation study of pure β-TCP on magnesium
  11. Pharmaceutical microparticle engineering with electrospraying: the role of mixed solvent systems in particle formation and characteristics
  12. Preparation and characterization of biphasic calcium phosphate ceramics of desired composition
  13. Safety and efficacy of a novel abluminal groove-filled biodegradable polymer sirolimus-eluting stent
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  18. Hydrolysis of monetite/chitosan composites in α-MEM and SBF solutions
  19. Apatite-forming PEEK with TiO 2 surface layer coating
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