Authors: Fumihide Itokawa Takao Itoi Atsushi Sofuni Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Reina Tanaka Naoyuki Yokoyama Fuminori Moriyasu Kazuhiko Kasuya Toshitaka Nagao Terumi Kamisawa Akihiko Tsuchida
Publish Date: 2011/04/20
Volume: 46, Issue: 6, Pages: 843-853
Abstract
Recently the usefulness of endoscopic ultrasound EUS elastography has been reported for the diagnosis of pancreatic lesions In the present study we retrospectively assessed EUS elastography as a diagnostic tool by evaluating tissue elasticity distribution and elasticity semiquantification using the strain ratio SR of tissue elasticity in patients with pancreatic massesOne hundred and nine patients who underwent EUS elastography between September 2006 and May 2009 were retrospectively evaluated The final diagnosis was chronic pancreatitis CP in 20 patients 6 with nonmassforming pancreatitis 7 with massforming pancreatitis MFP and 7 with autoimmune pancreatitis AIP pancreatic cancer PC in 72 pancreatic neuroendocrine tumor PNET in 9 and normal pancreas in 8 The tissue elasticity distribution calculation was performed in real time and the results were represented in color in fundamental Bmode imaging In addition we performed quantification using the SR nonmass area/mass areaElastography for all PC patients showed intense blue coloration indicating malignant lesions In contrast MFP presented with a mixed coloration pattern of green yellow and lowintensity blue Normal controls showed an even distribution of green to red The mean SR was 2366 ± 1265 for MFP and 3908 ± 2054 for PC P 005
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