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Title of Journal: J Gastroenterol

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Abbravation: Journal of Gastroenterology

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Springer Japan

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DOI

10.1002/jsfa.2740271210

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1435-5922

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Hybrid training of voluntary and electrical muscle

Authors: Takumi Kawaguchi Naoto Shiba Takashi Maeda Toru Matsugaki Yoshio Takano Minoru Itou Masahiro Sakata Eitaro Taniguchi Kensei Nagata Michio Sata
Publish Date: 2011/02/22
Volume: 46, Issue: 6, Pages: 746-757
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Abstract

Physical inactivity is a risk factor for the development of nonalcoholic fatty liver disease NAFLD “Hybrid training” a training that involves both voluntary and electrical muscle contractions causes beneficial alterations in muscles even after short durations of exercise The aim of this study was to investigate the therapeutic efficacy of hybrid training in patients with NAFLDThirtyfive patients with NAFLD who were resistant to lifestyle counseling were assigned to a hybridtraining group n = 12 or a control group n = 23 In the hybridtraining group quadriceps and hamstrings were contracted voluntarily or electrically for 19 min twice a week In the control group patients received lifestyle counseling The therapeutic efficacy of the hybrid training was evaluated after 12 weeks of the interventionSerum alanine aminotransferase ALT levels and hepatic steatosis grade were significantly decreased in the hybridtraining group compared to that of the control group −141 ± 58 vs 35 ± 54 IU/mL P  005 −067 ± 019 vs 009 ± 006 grade P  001 respectively No significant changes were seen between the two groups in skeletal muscle mass The decreases in homeostasis model assessment of insulin resistance HOMAIR value and in serum IL6 levels were significantly greater in the hybridtraining group than in the control group −62 ± 32 vs 04 ± 06 P  005 −31 ± 11 vs 11 ± 05 pg/mL P  001 respectively

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