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Title of Journal: Bioprocess Biosyst Eng

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Abbravation: Bioprocess and Biosystems Engineering

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Springer Berlin Heidelberg

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DOI

10.1002/jlac.18540920319

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1615-7605

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Sensitive change of isobranched fatty acid iso1

Authors: DaHye Yi Ganesan Sathiyanarayanan Hyung Min Seo JungHo Kim Shashi Kant Bhatia YunGon Kim SungHee Park JiYoung Jung Yoo Kyung Lee YungHun Yang
Publish Date: 2015/11/13
Volume: 39, Issue: 1, Pages: 159-167
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Abstract

In this study the environmental adaptive metabolic processes were investigated using a psychrotrophic polar bacterium Bacillus pumilus PAMC 23174 in response to various temperatures and nutrients especially in regard to the synthesis of fatty acids Fatty acid methyl ester analysis was performed using gas chromatography–mass spectrometry and we found that a sensitive changes in isobranched fatty acid iso150 synthesis occurred when adjusting the nutritional ratio of branched chain fatty acids anteiso/iso with different temperatures resulting in a change in the balance of anteiso and isoform fatty acids We also observed that this Arctic bacterium preferred amino acid leucine for the synthesis of fatty acids The increased and decreased synthesis of isoform fatty acids in response to different temperatures and leucine preference changes the fatty acid ratio in bacteria which further affects the membrane fluidity and it is also directly correlated with survival of bacteria in an extreme environment Hence this study suggests that B pumilus PAMC 23174 is a potential model organism for the analysis of the unique ecological adaptations of polar bacteria in changing and the extreme environmentsThe study was partially supported by the National Research Foundation of Korea NRF funded by the Ministry of Education NRF2015M1A5A1046168 NRF2015M1A5A1037196 and Korea Polar Research Institute PE15030 This research was supported by Advanced Production Technology Development Program Ministry of Agriculture Food and Rural Affairs Republic of Korea 1201349190011 and the Energy Efficiency Resources of the Korea Institute of Energy Technology Evaluation and Planning KETEP grant funded by the Korea Government Ministry of Trade Industry and Energy 20133030000300


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