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Title of Journal: Eur J Clin Pharmacol

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Abbravation: European Journal of Clinical Pharmacology

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Springer-Verlag

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DOI

10.1007/s40305-015-0091-1

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1432-1041

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Mirtazapine in druginduced excessive sweating

Authors: Ansgar Buecking Caroline Louise Vandeleur Yasser Khazaal Daniele Fabio Zullino
Publish Date: 2005/07/09
Volume: 61, Issue: 7, Pages: 543-544
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Abstract

Excessive sweating is a wellknown side effect of a selective serotonin reuptake inhibitor treatment but little is known about the impact of sweating on treatment discontinuation or the general quality of life of patients In this case report we present a patient suffering from excessive sweating induced by escitalopram When mirtazapine was administered as an additional treatment a dosedependent reduction of druginduced excessive sweating was observed Taking into account the particular serotonin antagonistic properties of mirtazapine its eventual influence on the regulation of body temperature and diaphoresis in the central nervous system is discussed

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