Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Eur J Clin Pharmacol

Search In Journal Title:

Abbravation: European Journal of Clinical Pharmacology

Search In Journal Abbravation:

Publisher

Springer Berlin Heidelberg

Search In Publisher:

ISSN

1432-1041

Search In ISSN:
Search In Title Of Papers:

Influence of bariatric surgery on the use of medic

Authors: Jan Peter Yska Douwe H van der Meer Albert R Dreijer Willeke Eilander Jan A Apers Marloes Emous Erik R E Totté Bob Wilffert Eric N van Roon
Publish Date: 2015/11/03
Volume: 72, Issue: 2, Pages: 203-209
PDF Link

Abstract

Bariatric surgery can influence the prevalence and incidence of comorbidities as well as the pharmacokinetics of drugs This might lead to changes in the use of drugs This study aimed to assess the influence of bariatric surgery on the use of medication in patients before and after surgery focusing on type number of medications and daily dosageIn a retrospective and prospective observational study drug dispensing data from pharmacies of patients undergoing their first bariatric surgery between January 2008 and September 2011 was collected Dispensing data from 1 month before until 12 months after surgery was analyzed Drugs were classified according to the WHOATC classification system Dosages of drugs were compared using defined daily dose DDDAmong 450 patients 12 months after surgery the mean number of drugs per patient for antidiabetics drugs acting on the cardiovascular system antiinflammatory and antirheumatic drugs and drugs for obstructed airway diseases decreased by respectively 713  95  CI 572 to 854 345  95  CI 282 to 430 455  95  CI 133 to 726 and 331  95  CI 153 to 532 Patients used lower median DDD of oral antidiabetics betablocking agents and lipidmodifying drugsFor some major drug classes 12 months after bariatric surgery the use of drugs decreases in terms of mean number per patient A reduction in dose intensity was observed for oral antidiabetics betablocking agents and lipidmodifying drugs Dispensing data from pharmacies may provide detailed information on the use of medications by patients after bariatric surgeryResults from this study were presented in part in an oral presentation at the Jahrestagung 2014 DGPT Deutsche Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie in April 2014 NaunynSchmiedeberg’s Archives of Pharmacology 2014 3 Suppl 1S223

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Real-time RT-PCR methodology for quantification of thiopurine methyltransferase gene expression
  2. Impact of the CYP2D6 polymorphism on steady-state plasma concentrations and clinical outcome of donepezil in Alzheimer’s disease patients
  3. Polymorphisms of dopamine receptor genes and risk of visual hallucinations in Parkinson’s patients
  4. Linezolid-related haematological toxicity in a peritoneal dialysis patient: the role of therapeutic drug monitoring
  5. Antibiotic prescription and prevalence rate in the outpatient paediatric population: analysis of surveys published during 2000–2005
  6. Relationship between CYP3A activity and breast cancer susceptibility in Chinese Han women
  7. Psychological and physiological effects of bupropion compared to methylphenidate after prolonged administration in healthy volunteers (NCT00285155)
  8. Incidence and risk factors for nevirapine-associated rash
  9. Case series: paradoxical action of domperidone leads to increased vomiting
  10. Lovastatin and thalidomide have a combined effect on the rate of multiple myeloma cell apoptosis in short term cell cultures
  11. Effect of ciprofloxacin on the pharmacokinetics of ropivacaine
  12. Ile118Val genetic polymorphism of CYP3A4 and its effects on lipid-lowering efficacy of simvastatin in Chinese hyperlipidemic patients
  13. Orphan drugs, orphan diseases. The first decade of orphan drug legislation in the EU
  14. Increased frequency of CYP2C9 variant alleles and homozygous VKORC1*2B carriers in warfarin-treated patients with excessive INR response
  15. Laxative treatment elevates plasma homocysteine: a study on a population-based Swedish sample of old people
  16. Clinical pharmacology of melatonin in the treatment of tinnitus: a review
  17. Network meta-analysis of first- and second-generation protease inhibitors for chronic hepatitis C genotype 1: efficacy based on RVR and SVR 24
  18. Lack of association between SLCO1B1 polymorphism and the lipid-lowering effects of atorvastatin and simvastatin in Chinese individuals
  19. Obesity is associated with a slower response to initial phenprocoumon therapy whereas CYP2C9 genotypes are not
  20. Obesity is associated with a slower response to initial phenprocoumon therapy whereas CYP2C9 genotypes are not
  21. Effects of CYP2C19 and CYP2C9 genotypes on pharmacokinetic variability of valproic acid in Chinese epileptic patients: nonlinear mixed-effect modeling
  22. Off-label use of anticancer drugs in eastern Switzerland: a population-based prospective cohort study
  23. Clinical trials during pregnancy: what has been done
  24. Thiopurine S-methyltransferase activity in three major Asian populations: a population-based study in Singapore
  25. Pharmacokinetic–pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/benserazide
  26. Mechanism-based population pharmacokinetic and pharmacodynamic modeling of intravenous and intranasal dexmedetomidine in healthy subjects
  27. A randomised cross-over study on the haemodynamic effects of oral dofetilide compared with oral sotalol in patients with ischaemic heart disease and sustained ventricular tachycardia
  28. Who volunteers for phase I clinical trials? Influences of anxiety, social anxiety and depressive symptoms on self-selection and the reporting of adverse events
  29. Comparison of rational pharmacotherapy decision-making competence of general practitioners with intern doctors
  30. Fluconazole but not the CYP3A4 inhibitor, itraconazole, increases zafirlukast plasma concentrations
  31. Pharmacokinetic study of the interaction between itraconazole and nevirapine
  32. Mirtazapine in drug-induced excessive sweating
  33. Population pharmacokinetic analysisof lamivudine, stavudine and zidovudine in controlled HIV-infected patients on HAART
  34. Diosmin pretreatment affects bioavailability of metronidazole
  35. Associations between CYP2E1 promoter polymorphisms and plasma 1,3-dimethyluric acid/theophylline ratios
  36. Long-term neurocognitive effects of antipsychotics in schizophrenia: a network meta-analysis
  37. Biosimilar erythropoiesis-stimulating agents and the risk of developing anti-drug antibodies—a systematic review
  38. Early discontinuation: more frequent among general practitioners with high levels of prescribing
  39. Stimulation of endothelial progenitor cells: a new putative effect of several cardiovascular drugs
  40. Medical speciality and pattern of medicines prescription
  41. Identification of cytochrome P450 isoforms involved in the metabolism of loperamide in human liver microsomes
  42. Herbal medicines – they are popular, but are they also safe?
  43. Restricted indications for the use of antibiotics in acute otitis media
  44. Motives for reporting adverse drug reactions by patient-reporters in the Netherlands
  45. The effect of acarbose on the pharmacokinetics of rosiglitazone
  46. Use of psychotropics is high among very old people
  47. Benzodiazepine use in the real world of psychiatric practice: low-dose, long-term drug taking and low rates of treatment discontinuation
  48. Prevalence of statin-drug interactions in older people: a systematic review
  49. Vitamin D deficiency as adverse drug reaction? A cross-sectional study in Dutch geriatric outpatients
  50. Use of anti-asthmatic drugs during pregnancy. 1. Maternal characteristics, pregnancy and delivery complications
  51. Factors influencing the pharmacokinetics of prophylactic posaconazole oral suspension in patients with acute myeloid leukemia or myelodysplastic syndrome
  52. Oral quinine pharmacokinetics and dietary salt intake
  53. Hemodynamics and pharmacokinetics of tezosentan, a dual endothelin receptor antagonist, in patients with cirrhosis
  54. Children’s presence in research. A review of online registers
  55. Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers
  56. Evidence of safety of chloral hydrate for prolonged sedation in PICU in a tertiary teaching hospital in southern Brazil
  57. Genistein alters caffeine exposure in healthy female volunteers
  58. Merck fellowships contribute to the continued growth of clinical pharmacology in Sweden
  59. Concomitant antibiotic usage does not augment the risk of inflammatory bowel disease with isotretinoin treatment for acne: a review of the Food and Drug Administration Adverse Event Reporting System
  60. Pharmacokinetics of midazolam in CYP3A4- and CYP3A5-genotyped subjects
  61. Novel strategies for the treatment of inflammatory hyperalgesia
  62. Germ line polymorphisms as predictive markers for pre-surgical radiochemotherapy in locally advanced rectal cancer: a 5-year literature update and critical review
  63. The pharmacokinetic profile of fesoterodine 8 mg with daytime or nighttime dosing
  64. The pharmacokinetic profile of fesoterodine 8 mg with daytime or nighttime dosing
  65. Rifampicin markedly decreases the exposure to oral and intravenous tramadol
  66. Potentially inappropriate prescribing in elderly outpatients in Croatia
  67. Challenges in collecting pharmacokinetic and pharmacodynamic information in an intensive care setting: PK/PD modelling of clazosentan in patients with aneurysmal subarachnoid haemorrhage
Search Result: