Authors: M A Grillo S Colombatto
Publish Date: 2007/03/03
Volume: 34, Issue: 2, Pages: 187-193
Abstract
Sadenosylmethionine is involved in many processes mainly methylation polyamine synthesis and radicalbased catalysis It is synthesised through the catalysis of differently regulated enzyme forms When it is used the compounds formed are reutilized in different ways in case of methylation its end product is homocysteine which can be remethylated to methionine give rise to cysteine in the socalled transsulphuration pathway or be released in the case of polyamine synthesis the methylthioadenosine formed is cleaved and gives rise to compounds which can be reutilized during radicalbased catalysis 5deoxyadenosine is formed and this too is cleaved and reutilized
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