Authors: Almino C Ramos Manoel P Galvão Neto Yglésio Moyses de Souza Manoela Galvão Abel H Murakami Andrey C Silva Edwin G Canseco Raúl Santamaría Trino A Zambrano
Publish Date: 2008/11/06
Volume: 19, Issue: 3, Pages: 307-312
Abstract
The association between medical and dietetic–behavioral treatments of type 2 diabetes mellitus T2DM has demonstrated to have variable results The surgical treatment of T2DM is justifiable after the observation of a successful glycemic control in patients submitted to RouxenY gastric bypass and biliopancreatic diversion Experiments have shown an important role of the proximal intestine in glycemia decrease and diabetes controlThere was a BMI decrease up to the third month and a weight stabilization between the third and sixth months There was a significant reduction in fasting glycemia 438 and HbA1c 228 up to the sixth month p 0001 Cpeptide did not show any significant alteration until the third month although there was a considerable increase 25 between the third and the sixth months p 0001 Only two patients were on oral medication after the sixth monthPreliminary results have shown an important effect of the laparoscopic duodenal–jejunal exclusion in the treatment of T2DM Studies with longer followup and a larger number of patients are necessary to better define the role of this new and promising procedure
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