Authors: Marney A White Melissa A Kalarchian Michele D Levine Robin M Masheb Marsha D Marcus Carlos M Grilo
Publish Date: 2015/02/27
Volume: 25, Issue: 10, Pages: 1909-1916
Abstract
Three hundred fiftyseven patients completed a battery of assessments before and at 6 12 and 24 months following gastric bypass surgery In addition to weight loss and depressive symptoms the assessments targeted eating disorder psychopathology and quality of lifeClinically significant depressive symptoms defined as a score of 15 or greater on the Beck Depression Inventory characterized 45 of patients prior to surgery and 12 at 6month followup 13 at 12month followup and 18 at 24month followup Preoperative depressive symptoms did not predict postoperative weight outcomes In contrast postsurgery depressive symptoms were predictive of weight loss outcomes Higher postsurgery depressive symptoms at each time point predicted a greater degree of concurrent and subsequent eating disorder psychopathology and lower quality of lifeThe frequency of elevated depressive symptoms decreases substantially following gastric bypass surgery but increases gradually over 24 months Postoperative depressive symptoms are significantly associated with poorer weight outcomes at 6 and 12 months following surgery but do not predict longerterm weight outcomes at 24 months Postoperative depressive symptoms prospectively predict greater eating disorder psychopathology and poorer quality of life through 24 months Elevated depressive symptoms readily assessed by selfreport may signal a need for clinical attention after surgeryDr Kalarchian reports a grant from the National Institute of Health during the conduct of the study and grants from TOS/Nutrisystem grants from NIH/NIDDK and grants from ASMBS Foundation outside the submitted work Dr Grilo reports grants from National Institutes of Health during the conduct of the study grants from the National Institutes of Health and Medical research Foundations personal fees from Shire honoraria from the American Psychological Association various scientific conferences and universities for delivering research lectures and grand rounds and various CMErelated educational talks book royalties from Guilford Press Taylor Francis Publishers outside the submitted workAll procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards
Keywords: