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Title of Journal: OBES SURG

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Abbravation: Obesity Surgery

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Springer US

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DOI

10.1007/978-3-540-24654-1_17

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ISSN

1708-0428

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Duodenal–Jejunal Bypass Improves Glucose Metabolis

Authors: Chunxiao Hu Guangyong Zhang Dong Sun Haifeng Han Sanyuan Hu
Publish Date: 2013/05/01
Volume: 23, Issue: 9, Pages: 1436-1444
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Abstract

There is accumulating evidence that adipokines lead to a proinflammatory state which plays crucial roles in insulin resistance and development of type 2 diabetes mellitus T2DM Previous studies demonstrated that weight loss after bariatric surgery is accompanied by a suppression of the proinflammatory state However the effect of bariatric surgery on adipokine expression beyond weight loss is still elusive The aim of this study was to investigate the effect of duodenal–jejunal bypass DJB on glucose homeostasis and adipokine expression independently of weight lossA T2DM rat model was developed by a highfat diet and low dose of streptozotocin Twentyone diabetic rats and 10 agematched SD rats were randomly assigned to the DJB group shamDJB SDJB group and control group For 12 weeks after surgery their body weight food intake glucose homeostasis lipid parameters serum adipokine levels and adipokine gene expression in the mesocolon adipose tissue were measuredCompared to the SDJB group DJB induced significant and sustained glycemic control with improved insulin sensitivity and glucose tolerance independently of weight loss DJB improved the lipid metabolism by decreasing fasting free fatty acids and triglycerides Serum leptin and IL6 significantly decreased 12 weeks after DJB whereas adiponectin increased and TNFα remained unchanged The mRNA expression levels of leptin TNFα and IL6 decreased whereas adiponectin increased in the mesocolon adipose tissueThis work was supported by the National Natural Science Foundation of China no 81270888/H0713 and no 81070642/H0713 Specialized Research Fund for the Doctoral Program of Higher Education no 20100131110049 Shandong Provincial Outstanding Medical Academic Professional Program Natural Science Foundation of Shandong Province grants no ZR2012HQ030 and Graduate Independent Innovation Foundation of Shandong University noyzc12160 Thanks to Dr Edward C Mignot Shandong University and EDANZ a professional language service for linguistic advice

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Other Papers In This Journal:
  1. Determinants of Hyperhomocysteinemia After Gastric Bypass Surgery in Obese Subjects
  2. Long-Term Experience with Duodenal Switch in Adolescents
  3. Preoperative Nutritional Interventions in Morbid Obesity: Impact on Body Weight, Energy Intake, and Eating Quality
  4. Robotic Sleeve Gastrectomy Versus Laparoscopic Sleeve Gastrectomy: a Comparative Study with 200 Patients
  5. Psychological Considerations for Bariatric Surgery among Older Adults
  6. Early Post-operative Complications: Incidence, Management, and Impact on Length of Hospital Stay. A Retrospective Comparison Between Laparoscopic Gastric Bypass and Sleeve Gastrectomy
  7. Changes in Ghrelin Levels Following Bariatric Surgery: Review of the Literature
  8. A Noninvasive Clinical Scoring Model Predicts Risk of Nonalcoholic Steatohepatitis in Morbidly Obese Patients
  9. Banded Sleeve Gastrectomy—Initial Experience
  10. Reply to the article Espinós JC, Turró R, Mata A, Cruz M, da Costa M, Villa V, Buchwald JN, Turró J. Early Experience with the Incision less Operating Platform™ (IOP) for the Treatment of Obesity: The Primary Obesity Surgery Endolumenal (POSE) Procedure. Obes Surg. 2013;23:1375–83
  11. Effect of Weight Loss following Bariatric Surgery on Myocardial Dispersion of Repolarization in Morbidly Obese Patients
  12. Chronic Renin–Angiotensin System (RAS) Blockade May Not Induce Hypotension During Anaesthesia for Bariatric Surgery
  13. Retinol and α-Tocopherol in Morbid Obesity and Nonalcoholic Fatty Liver Disease
  14. Laparoscopic Duodenal–Jejunal Exclusion in the Treatment of Type 2 Diabetes Mellitus in Patients with BMI < 30 kg/m 2 (LBMI)
  15. Progress in Implantable Gastric Stimulation: Summary of Results of the European Multi-Center Study
  16. A Retrospective Review of the Medical Management of Hypertension and Diabetes Mellitus Following Sleeve Gastrectomy
  17. Integrated Bioabsorbable Tissue Reinforcement in Laparoscopic Sleeve Gastrectomy
  18. Response to Letter to the Editor Re: The Effect of PPI Use on Human Gut Microbiota and Weight Loss in Patients Undergoing Laparoscopic Roux-en-Y Gastric Bypass
  19. Evaluation of Clinical Outcomes for Gastric Bypass Surgery: Results from a Comprehensive Follow-up Study
  20. Bio-enteric Intragastric Balloon in Obese Patients: A Retrospective Analysis of King Faisal Specialist Hospital Experience
  21. Comparative Study Between Laparoscopic Adjustable Gastric Banded Plication and Sleeve Gastrectomy in Moderate Obesity—2 Year Results
  22. A Nationwide Survey on Bariatric Surgery in Germany—Results 2005–2007
  23. Prognostic Significance of Depressive Symptoms on Weight Loss and Psychosocial Outcomes Following Gastric Bypass Surgery: A Prospective 24-Month Follow-Up Study
  24. Laparoscopic Magenstrasse and Mill Gastroplasty. First Results of a Prospective Study
  25. Influence of -55CT Polymorphism of UCP3 Gene on Surgical Results of Biliopancreatic Diversion
  26. Impact of Weight Loss Due to Sleeve Gastrectomy on Shear Stress of the Femoral Vein in Morbid Obesity
  27. Comparison Between the Results of Laparoscopic Sleeve Gastrectomy and Laparoscopic Roux-en-Y Gastric Bypass in the Indian Population: A Retrospective 1 Year Study
  28. Laparoscopic Sleeve Gastrectomy in Ethnic Obese Chinese
  29. Comparison of Volume-controlled and Pressure-controlled Ventilation during Laparoscopic Gastric Banding in Morbidly Obese Patients
  30. Laparoscopic Sleeve Gastrectomy with Duodenojejunal Bypass for the Treatment of Type 2 Diabetes in Non-obese Patients: Technique and Preliminary Results
  31. Laparoscopic Adjustable Gastric Banding: a Prospective Randomized Clinical Trial Comparing 5-Year Results of two Different Bands in 103 Patients
  32. Psychological Correlates of Laparoscopic Adjustable Gastric Band and Gastric Bypass Patients
  33. Preoperative Weight Loss with Intragastric Balloon Decreases the Risk of Significant Adverse Outcomes of Laparoscopic Gastric Bypass in Super-Super Obese Patients
  34. Reconstructive Procedures after Massive Weight Loss
  35. Use of Foley’s Catheter to Control Port-Site Bleeding in Bariatric Surgery
  36. Single-Incision Laparoscopic Adjustable Gastric Banding is Effective and Safe: 756 Cases in an Academic Medical Center
  37. Apelin Levels Are Increased in Morbidly Obese Subjects with Type 2 Diabetes Mellitus
  38. Morphofunctional Evaluation of the Heart of Obese Patients Before and After Bariatric Surgery
  39. Laparoscopic Conversion of Roux-en-Y Gastric Bypass to Sleeve Gastrectomy As First Step of Duodenal Switch: Technique and Preliminary Outcomes
  40. Risk-Group Targeted Inferior Vena Cava Filter Placement in Gastric Bypass Patients
  41. Endoscopic Management of Vertical Banded Gastroplasty Stricture: Feasibility, Safety, and Efficacy
  42. Nutritional Consequences of Adjustable Gastric Banding and Gastric Bypass: A 1-year Prospective Study
  43. Bariatric Surgery, Safety and Type 2 Diabetes
  44. Lethal Intestinal Perforation After Foreign Body Ingestion in a Superobese Patient
  45. Satisfaction and Quality-of-Life Issues in Body Contouring Surgery Patients: a Qualitative Study
  46. Lifestyle Modification Parallels to Sleeve Success
  47. Comparison of Serum and Salivary Ghrelin in Healthy Adults, Morbidly Obese, and Patients with Metastatic Carcinoma
  48. Different Effect of Laparoscopic Roux-en-Y Gastric Bypass and Open Biliopancreatic Diversion of Scopinaro on Serum PYY and Ghrelin Levels
  49. Single Port Trans-gastric Reversal of High Gastric Reduction
  50. Depletion of Serum Carotenoid and Other Fat-Soluble Vitamin Concentrations following Obesity Surgery
  51. Gastric Emptying of Semisolids and Pouch Motility Following Laparoscopic Adjustable Gastric Banding
  52. The Preceding Surgeon Factor in Bariatric Surgery: a Positive Influence on the Learning Curve of Subsequent Surgeons
  53. Preoperative 4-Week Low-Calorie Diet Reduces Liver Volume and Intrahepatic Fat, and Facilitates Laparoscopic Gastric Bypass in Morbidly Obese
  54. An Unusual Suspect: Coconut Bezoar After Laparoscopic Roux-en-Y Gastric Bypass
  55. Referral for a Bariatric Surgical Consultation: It is Time to Set a Standard of Care
  56. Efficacy of a Laparoscopic Gastric Restrictive Device in an Obese Canine Model
  57. Laparoscopic vs Open Gastric Bypass in the Management of Morbid Obesity: A 7-year Retrospective Study of 1,364 Patients from a Single Center
  58. Adherence and Weight Loss Outcomes in Bariatric Surgery: Does Cognitive Function Play a Role?
  59. Gastric Wall Thickness and the Choice of Linear Staples in Laparoscopic Sleeve Gastrectomy: Challenging Conventional Concepts
  60. Changes in Lipid Profiles in Morbidly Obese Patients After Laparoscopic Sleeve Gastrectomy (LSG)
  61. Validating the Alterable Weight Loss (AWL) Metric with 2-Year Weight Loss Outcome of 500 Patients After Gastric Bypass
  62. Endoscopic Balloon Dilation of Stomal Stenosis following Gastric Bypass
  63. The Utility of the Beck Depression Inventory in a Bariatric Surgery Population
  64. FTO mRNA Expression in Extremely Obese and Type 2 Diabetic Human Omental and Subcutaneous Adipose Tissues
  65. Three-Year Follow-Up Study of Retrocolic versus Antecolic Laparoscopic Roux-en-Y Gastric Bypass
  66. Opioid Requirements after Laparoscopic Bariatric Surgery
  67. Sociodemographic Trends in Bariatric Surgery Utilization in the USA
  68. Myocardial Insulin Signaling and Glucose Transport Are Up-regulated in Goto–Kakizaki Type 2 Diabetic Rats After Ileal Transposition
  69. Response to “Banded Bypass”: The Way to Go?
  70. Combination of Bypassing Stomach and Vagus Dissection in High-Fat Diet-Induced Obese Rats—A Long-Term Investigation
  71. Preoperative Endoscopic Screening for Laparoscopic Roux-en-Y Gastric Bypass has a Low Yield for Anatomic Findings
  72. Are Knee and Foot Orthopedic Problems More Disabling in the Superobese?
  73. Perforator-Sparing Abdominoplasty Technique in the Presence of Bilateral Subcostal Scars after Gastric Bypass
  74. The Effects of Liposuction Removal of Subcutaneous Abdominal Fat on Lipid Metabolism are Independent of Insulin Sensitivity in Normal-Overweight Individuals
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