Authors: Carlos Zerrweck Vincent Maunoury Robert Caiazzo Julien Branche Guélareh Dezfoulian Philippe Bulois Helene Verkindt Marie Pigeyre Laurent Arnalsteen François Pattou
Publish Date: 2012/02/16
Volume: 22, Issue: 5, Pages: 777-782
Abstract
Extreme obesity increases morbimortality in bariatric surgery We previously showed that significant weight loss can be obtained within 3 months in supersuper obese patients BMI 60 kg/m2 with an intragastric balloon IGB Here we explored the potential benefit of preoperative IGB on the outcome of laparoscopic gastric bypass LGBP in supersuper obese patientsIn this case–control study we compared the records of 60 consecutive supersuper obese patients 665 ± 34 kg/m2 submitted to a LGBP between 2004 and 2009 with preoperative IGB n = 23 cases or without n = 37 controls We analyzed the clinical outcome of surgery and a composite end point of significant adverse events defined as the presence of at least one of the following conditions conversion to laparotomy intensive care unit stay for more than 2 days and overall hospital stay superior to 2 weeksAll baseline clinical and biological characteristics were homogenous between both groups IGB was maintained during 155 ± 62 days and induced a loss of 55 ± 13 kg/m2 112 ± 32 of excess body mass index at the time of LGBP associated with a decrease in systolic blood pressure and gammaglutamyl transpeptidase level p 005 vs baseline Operative time was lower in the IGB group 146 ± 47 vs 201 ± 81 min in controls p 001 Significant adverse events occurred less frequently after LGBP in the IGB group 2 vs 13 in controls p 005 All patients were alive at 1 year and overall weight loss was similar in both groups 524 ± 173 vs 503 ± 127 percent of excess BMI loss in controls NSAll contributing authors Carlos Zerrweck Vincent Maunoury Robert Caiazzo Julien Branche Guélareh Dezfoulian Philippe Bulois Helene Verkindt Marie Pigeyre Laurent Arnalsteen and François Pattou declare that they have no conflicts of interest
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