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Title of Journal: Cell Biochem Biophys

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Abbravation: Cell Biochemistry and Biophysics

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Humana Press Inc

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DOI

10.1007/s00231-017-1979-6

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ISSN

1559-0283

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Effects of Atorvastatin on Pathological Changes in

Authors: JingJing Cui Dong Wang Fei Gao YueRong Li
Publish Date: 2011/10/18
Volume: 62, Issue: 1, Pages: 87-90
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Abstract

To explore the effects of atorvastatin on hydrocephalus neurocyte apoptosis and the level of plasma matrix metalloproteinase9 MMP9 after intracerebral hemorrhage ICH in rats A rat model of ICH was established by intracerebral injection of collagenase The brain water content was determined by the wet/dry weight ratio ultrastructural changes in brain tissue were observed by electron microscopy and the level of plasma MMP9 was quantified by ELISA Atorvastatin showed significant effects in reducing the brain water content blocking neuron apoptosis and decreasing plasma MMP9 in rats with ICH There was a positive linear correlation between plasma MMP9 and the brain water content Atorvastatin can significantly relieve brain edema decrease the brain injury caused by MMP9 and protect neurons in rats with ICH

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  2. Growth Inhibition and Apoptosis of Neuroblastoma Cells Through ROS-Independent MEK/ERK Activation by Sulforaphane
  3. Biochemical Characterization of the Detoxifying Enzyme Glutathione Transferase P1-1 from the Camel Camelus Dromedarius
  4. Spectroscopic Determination of Lysozyme Conformational Changes in the Presence of Trehalose and Guanidine
  5. The NAD World: A New Systemic Regulatory Network for Metabolism and Aging—Sirt1, Systemic NAD Biosynthesis, and Their Importance
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  7. Clinical Factors Associated With the Diagnosis and Progression of Diabetic Nephropathy
  8. Experimental Studies on the Inhibition of Adenovirus-ING4-OSM Therapy on Nasopharyngeal Carcinoma Proliferation In Vitro and In Vivo
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  10. Evaluation of Stem Cell-to-Tenocyte Differentiation By Atomic Force Microscopy to Measure Cellular Elastic Moduli
  11. Influence of Novel Nano-Mesoporous Bioactive Glass on the Regulation of IGF-II Gene Expression in Osteoblasts
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