Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Cell Biochem Biophys

Search In Journal Title:

Abbravation: Cell Biochemistry and Biophysics

Search In Journal Abbravation:

Publisher

Springer US

Search In Publisher:

DOI

10.1007/bf02389823

Search In DOI:

ISSN

1559-0283

Search In ISSN:
Search In Title Of Papers:

The Attenuation of Lung Ischemia Reperfusion Injur

Authors: Bing Zhu JianRu Yang ShiFeng Chen Yue Quan Jiang
Publish Date: 2014/04/03
Volume: 70, Issue: 1, Pages: 333-336
PDF Link

Abstract

To investigate the protective effects of oxymatrine OMT on lung ischemia reperfusion injury LIRI in rabbits models of LIRI in rabbit were used Thirtytwo rabbits were randomly divided into four groups control group n = 8 ischemia reperfusion group I/R group n = 8 OMTl group n = 8 OMT2 group n = 8 Lung tissue samples were collected at 40 80 120 min timepoints after lung ischemia reperfusion TNFα 1I8 IL10 apoptosis index AI and index of quantitative assessment of histologic lung injury IQA were measured in each group TNFα and IL8 in I/R group were significantly higher than those of the control group and OMT2 group P  001 but in OMT2 group they were significantly lower than those of OMTl group P  005 IL10 in OMT2 group and OMTl group was significantly higher than that of I/R group P  001 But in OMTl group it was significantly lower than that of OMT2 group P  005 AI in I/R group was significantly higher than that of OMT2 group and the control group at 80 min after lung ischemia reperfusion P  001 IQA in OMTl group and OMT2 group was significantly lower than that of the I/R group P  001 Oxymatrine can protect against LIRI in rabbits by upregulating levels of IL10 and downregulating levels of TNFα and IL8 inhibiting the alveolar cells apoptosis and inflammatory response and attenuating the acute LIRIThis study was supported by the National Natural Sciences Foundation of China Grant No 30471984 the Foundation of Bureau of Public Health of Chongqing Grants 062001 06B26 and 20102127 and the project Innovation of Science and Technology Chongqing Science and Technology Commission Project No cstc2013jcyjA10108

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Oxymatrine Extracted from Sophora flavescens Inhibited Cell Growth and Induced Apoptosis in Human Osteosarcoma MG-63 Cells In Vitro
  2. Growth Inhibition and Apoptosis of Neuroblastoma Cells Through ROS-Independent MEK/ERK Activation by Sulforaphane
  3. Biochemical Characterization of the Detoxifying Enzyme Glutathione Transferase P1-1 from the Camel Camelus Dromedarius
  4. Spectroscopic Determination of Lysozyme Conformational Changes in the Presence of Trehalose and Guanidine
  5. The NAD World: A New Systemic Regulatory Network for Metabolism and Aging—Sirt1, Systemic NAD Biosynthesis, and Their Importance
  6. The Value of Multi-slice CT Imaging in Cardiac Myxomas in Comparison with Follow-Up Screening in Thoracoscopic Surgery
  7. Clinical Factors Associated With the Diagnosis and Progression of Diabetic Nephropathy
  8. Experimental Studies on the Inhibition of Adenovirus-ING4-OSM Therapy on Nasopharyngeal Carcinoma Proliferation In Vitro and In Vivo
  9. A Novel Urinary Metabolite Signature for Non-invasive Post-stroke Depression Diagnosis
  10. Evaluation of Stem Cell-to-Tenocyte Differentiation By Atomic Force Microscopy to Measure Cellular Elastic Moduli
  11. Effects of Atorvastatin on Pathological Changes in Brain Tissue and Plasma MMP-9 in Rats with Intracerebral Hemorrhage
  12. Influence of Novel Nano-Mesoporous Bioactive Glass on the Regulation of IGF-II Gene Expression in Osteoblasts
  13. Association with Leptin Gene c.-2548 G>A Polymorphism, Serum Leptin Levels, and Body Mass Index in Turkish Obese Patients
  14. Transglutaminase-2 is Involved in Cell Apoptosis of Osteosarcoma Cell Line U2OS Under Hypoxia Condition
  15. Gamma-Aminobutyric Acid Induces Tumor Cells Apoptosis via GABA B R1·β-Arrestins·JNKs Signaling Module
  16. Hypothesis: Tim-3/Galectin-9, A New Pathway for Leukemia Stem Cells Survival by Promoting Expansion of Myeloid-Derived Suppressor Cells and Differentiating into Tumor-Associated Macrophages
  17. Effects of NMDA-Receptor Antagonist on the Expressions of Bcl-2 and Bax in the Subventricular Zone of Neonatal Rats with Hypoxia–Ischemia Brain Damage
  18. Sema4D Knockdown in Oligodendrocytes Promotes Functional Recovery After Spinal Cord Injury
  19. An EP4 Antagonist ONO-AE3-208 Suppresses Cell Invasion, Migration, and Metastasis of Prostate Cancer
  20. Association of Arterial Oxygen Saturation and Acute Mountain Sickness Susceptibility: A Meta-analysis
  21. GJB2 as Well as SLC26A4 Gene Mutations are Prominent Causes for Congenital Deafness
  22. “One-off” Complete Radiofrequency Ablation of Hepatocellular Carcinoma Adjacent to the Gallbladder by a Novel Laparoscopic Technique Without Gallbladder Isolation
  23. Modulation, Bioinformatic Screening, and Assessment of Small Molecular Peptides Targeting the Vascular Endothelial Growth Factor Receptor
  24. Mechanism of Two Novel Human GJC3 Missense Mutations in Causing Non-Syndromic Hearing Loss
  25. Effects of Traditional Chinese Medicine Fu Zheng Decoction on the Immunological Function and Clinical Prognosis of the Elderly Patients with Pneumonia
  26. Endostatin Combined with Platinum-Based Chemo-radiotherapy for Advanced Non-small Cell Lung Cancer
  27. Autopsy Report of a 7-Year Old Patient with the Mosaic Trisomy 13
  28. Arthroscopic Tenodesis Through Positioning Portals to Treat Proximal Lesions of the Biceps Tendon
  29. Quantitative Redox Biology: An Approach to Understand the Role of Reactive Species in Defining the Cellular Redox Environment
  30. Neutrophils Play a Crucial Role in the Early Stage of Nonalcoholic Steatohepatitis via Neutrophil Elastase in Mice
Search Result: