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Title of Journal: FEMS Microbiol Lett

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Abbravation: FEMS Microbiology Letters

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Narnia

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DOI

10.1002/ange.19971090514

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0378-1097

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Control of the activity of the soluble lytic trans

Authors: Betzner AS Ferreira LCS Höltje JV Keck W
Publish Date: 1990/01/01
Volume: 67, Issue: 1-2, Pages: 161-164
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Abstract

AS Betzner LCS Ferreira JV Höltje W Keck Control of the activity of the soluble lytic transglycosylase by the stringent response in Escherichia coli FEMS Microbiology Letters Volume 67 Issue 12 January 1990 Pages 161–164 https//doiorg/101111/j157469681990tb13855xThe soluble lytic transglycosylase Slt of Escherichia coli is known to be a powerful murein hydrolase in vitro It is shown here to act as an autolysin in vivo as well Rapid autolysis of Slt overproducing cells was induced by protein biosynthesis inhibitors which also block the fomration of guanosine5′diphosphate3′diphosphate ppGpp When amino acid starvation was used to in relA+ but not in relA− cells These findings indicate that the stringent control modulates the enzymatic activity of the soluble lytic transglycosylase in vivo

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References

citation author=Shand RF citation author=Blum PH citation author=Mueller RD citation author=Riggs DL citation author=Artz SW citation journal title=J Bacteriol citation year=1989 citation volume=171 citation pages=737743

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