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Title of Journal: Comp Clin Pathol

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Abbravation: Comparative Clinical Pathology

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Springer-Verlag

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DOI

10.1002/cjce.21763

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1618-565X

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The dextran sulphate sodium DSS model of colitis

Authors: Livingstone Solomon Sorsiah Mansor Peter Mallon Eilish Donnelly Margaret Hoper Morris Loughrey Stephen Kirk Keith Gardiner
Publish Date: 2010/03/04
Volume: 19, Issue: 3, Pages: 235-239
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Abstract

The dextran sulphate sodium model of colitis has demonstrated several correlations with human inflammatory bowel disease and is deemed suitable for investigating pathogenesis therapeutic options and the dysplasia–adenocarcinoma sequence of inflammatory bowel disease It is widely applicable to mice rats hamsters and guinea pigs This review explores the features of this model and identifies areas for further research studies


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