Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Comp Clin Pathol

Search In Journal Title:

Abbravation: Comparative Clinical Pathology

Search In Journal Abbravation:

Publisher

Springer London

Search In Publisher:

DOI

10.1016/0038-1098(90)90985-k

Search In DOI:

ISSN

1618-565X

Search In ISSN:
Search In Title Of Papers:

Glutathione Emphasis Type="Italic"S/Emphasist

Authors: Mona W Ayad Dalia A Nafea
Publish Date: 2013/04/21
Volume: 23, Issue: 4, Pages: 1023-1029
PDF Link

Abstract

The aim of the present study was to detect the frequency of monosomy 7 and trisomy 8 in myeloid disorders acute myeloblastic leukemia AML myelodysplastic syndrome MDS their association with GSTT1 and GSTM1 null genotypes and their prognostic impact The study included 50 patients with AML and MDS monosomy 7 and trisomy 8 detection was done by interphase fluorescence in situ hybridization and glutathione Stransferase GST genotyping was done by multiplex PCR Monosomy 7 was present in 13–30 of AML and MDS respectively A statistically significant relation was found between monosomy 7 and remission failure Trisomy 8 was found in 10–15 of AML and MDS No significant association was found between response to treatment and trisomy 8 There was significant correlation between GSTT1 null/GSTM1 null genotype and poor response to treatment p 0005 There was positive correlation between complete remission and both wild GST genotypes In the whole patient group a statistically significant association was found between GSTT null genotypes and monosomy 7 p = 0003 No significant association was found between trisomy 8 and specific GST genotypic polymorphism

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. A histological study of the outer layer of rabbit fish ( Siganus javus ) eye
  2. Hereditary xanthinuria and urolithiasis in a domestic shorthair cat
  3. The dextran sulphate sodium (DSS) model of colitis: an overview
  4. Responses to training and standardised exercise test in the athlete horse: changes in blood gas profile
  5. Group B streptococcus colonization of pregnant women: comparative molecular and microbiological diagnosis
  6. Topical co-administration of flaxseed and pistachio ointment promoted wound healing; evidence for histopathological features
  7. A serological survey on Borrelia burgdorferi infection among companion dogs in Ahvaz district, southwestern Iran
  8. The effect of water-soluble fraction of crude oil on serum biochemical changes in the great sturgeon Huso huso
  9. Pathologic lesions of naturally occurring coccidiosis in sheep and goats
  10. Histometrical study of the different parts of ureter in one-humped camel
  11. Association of IL-10 gene promoter polymorphisms and non-Hodgkin lymphoma in Egyptian patients, relation to susceptibility, correlation with survival
  12. Effects of sutureless amniotic membrane patching with 2-Octyl cyanoacrylate (Dermabond) on experimental corneal alkali burn in dogs
  13. Detection of minimal residual disease (MRD) in canine lymphoma
  14. Sorghum stem extract modulates Na + /K + -ATPase, ecto-5′-nucleotidase, and acetylcholinesterase activities
  15. Determination of some normal serum parameters in starry sturgeon ( Acipenser stellatus Pallas, 1771) during spring season
  16. Experimental infection with Trypanosoma evansi in rams: presence of parasite in semen, investigation of sexual transmission, hematological, and biochemical alterations
  17. Effects of platelet-rich plasma (PRP) on cutaneous regeneration and wound healing in dogs treated with dexamethasone
  18. Articular cartilage changes in experimental osteoarthritis in rabbits: MRI and morphological findings
  19. Comparison of selected biochemical parameters between naturally infected and non-infected goats with Anaplasma ovis
  20. Metaplasia of the parietal layer of Bowman’s capsule in a cat
  21. Evaluation of wound healing activity of St. John’s Wort ( Hypericum perfoliatum ) in horses
  22. Prevalence of Coxiella burnetii in bovine bulk milk samples in southern Iran
  23. Osmotic fragility of human erythrocytes in vitro using Vipera lebetina venom
  24. Evaluation of changes in wound assessment parameters associated with contra-lateral spermatic cord as ligature in open and closed pre-scrotal and scrotal castrations
  25. Selected biochemical values of yearling African blue neck ostriches ( Struthio camelus ) in Iran
  26. Effect of a single intrastriatal rotenone injection on oxidative stress and neurodegeneration in the rat brain
  27. Antioxidant preserving effects of l -arginine at reducing the hemodynamic toxicity of gentamicin-induced rat nephrotoxicity: pathological and biochemical findings
  28. Clinical relevance of angiopoietin-1, angiopoietin-2, and their receptor Tie-2 expression in acute myeloid leukemia
  29. Clinical analyses of 379 Japanese and 2 non-Japanese patients with venous or arterial vascular diseases: combined B cell anomalies, gastric cancer, and aggravated ectopic splenosis
  30. Introduce Indian gray mongoose ( Herpestes edwardsii ): as a successful animal model for influenza virus infection (a preliminary study)
  31. Incidence of cardiomyopathy and collapse in two pregnant mares with history of subacute consumption of organophosphate-exposed Cynodon dactylon hay
  32. Effects of vitamin C on epididymal sperm quality following experimentally induced copper poisoning in mice
  33. Humoral immune response in Oreochromis niloticus : modified direct agglutination test
  34. Clinical aspects, morphometry, and morphology of blood cells of the emu ( Dromaius novaehollandiae ) reared in captivity
  35. Trichoepithelioma in a neonatal calf
  36. Maternal and offspring methylenetetrahydrofolate reductase gene C677T polymorphism: does it influence the prevalence of congenital heart defects in Egyptian neonates?
Search Result: