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Title of Journal: Comp Clin Pathol

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Abbravation: Comparative Clinical Pathology

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Springer London

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DOI

10.1007/bf02483728

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1618-565X

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Evaluation of wound healing activity of St John’s

Authors: Giudice Elisabetta Crinò Chiara Salerno Gaetano Rizzo Maria Levanti Maria Di Pietro Simona
Publish Date: 2017/02/15
Volume: 26, Issue: 3, Pages: 611-615
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Abstract

St John’s Wort SJW is an herbaceous medical plant Since ancient times SJW has been used to treat different kinds of mental and physical diseases and for its antiseptic antiinflammatory and antibacterial properties The aim of this study was to evaluate the wound healing activity of a phytotherapeutic product from St John’s Wort SJW herbaceous medical perennial plant on skin lesions of different origins in horses housed in Sicily Italy Six horses of different breeds age and attitude were enrolled in the study All the lesions were treated with an oil prepared from the aerial parts of Hypericum perfoliatum H perfoliatum macerated in oil under the sun Topical application of the oil determined a significant improvement of skin lesions in all the horses involved in the study Wound healing begun Time1 in a period ranging from 2 days to 2 weeks mean ± SD 4 ± 189 days The treatment resulted in complete resolution of wounds Time2 in a period between 1 and 5 weeks mean ± SD 145 ± 82 days while hair regrowth Time3 was completed in period between 25 days and 2 months mean ± SD 3325 ± 1258 days This study has certainly given a scientific point of view to a century of empiricism about the use of SJW in veterinary practice The findings of this study seem to suggest that SJW may be considered an “allinone” remedy for wound healing in order to make the management of skin injuries easier even for severe and complicated lesions


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