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Title of Journal: Clin Rheumatol

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Abbravation: Clinical Rheumatology

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Springer-Verlag

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DOI

10.1016/0034-5687(76)90073-6

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1434-9949

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Treatment of acute neuropsychiatric lupus with int

Authors: Aaron M Milstone Kevin Meyers Josephine Elia
Publish Date: 2005/01/21
Volume: 24, Issue: 4, Pages: 394-397
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Abstract

Neuropsychiatric lupus can be difficult to diagnose and little prospective data exists to help direct management In this case report we describe the acute onset of symptoms of depression mania and psychosis and their complete resolution 48 h following a 5day treatment course of intravenous immunoglobulin IVIG in a 20yearold woman with systemic lupus erythematosus SLE We review the literature on IVIG for the management of neuropsychiatric lupus We propose that when more toxic therapies are refused or symptoms do not remit with other treatments IVIG should be considered in patients with neuropsychiatric lupus

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