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Title of Journal: Clin Rheumatol

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Abbravation: Clinical Rheumatology

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Springer-Verlag

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1434-9949

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QT dispersion in uncomplicated familial Mediterran

Authors: Naomi Nussinovitch Avi Livneh Keren Katz Pnina Langevitz Olga Feld Moshe Nussinovitch Benjamin Volovitz Merav Lidar Udi Nussinovitch
Publish Date: 2010/04/11
Volume: 29, Issue: 12, Pages: 1353-1356
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Abstract

The aim of the study was to further evaluate repolarization dispersion in familial Mediterranean fever FMF Findings on 12lead electrocardiography were compared with 32 patients with uncomplicated FMF and age and sexmatched control subjects All procedures followed stringent standards Repolarization and dispersion parameters were computed with designated computer software and results of the five beats were subsequently averaged There were no statistically significant differences between the groups in average QT and average corrected QT interval length average QT interval dispersion average QT corrected dispersion or QT dispersion ratio During 6 months of followup no cases of sudden death or arrhythmia were documented in either group Patients with FMF who are continuously treated with lowdose colchicine and have not developed amyloidosis seem to have QT dispersion parameters similar to those of healthy subjects and therefore apparently have no increased risk of adverse cardiac events associated with abnormal repolarization

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