Authors: Ole R Madsen Anne Rytter Lonnie B Hansen Charlotte Suetta Charlotte Egsmose
Publish Date: 2010/03/21
Volume: 29, Issue: 8, Pages: 849-854
Abstract
The Bath Ankylosing Spondylitis Disease Activity Index BASDAI the Bath Ankylosing Spondylitis Function Index BASFI and the Bath Ankylosing Spondylitis Global Score BASG ranges 0–10 have gained widespread in use as selfreported measures of disease activity functional impairment and overall wellbeing in patients with ankylosing spondylitis and other spondyloarthropathies SpA In Denmark BASDAI BASFI and BASG are systematically used to monitor treatment response in patients treated with tumour necrosis factor TNF inhibitors The purpose of the present study was to examine the reproducibility of the indices in antiTNFtreated SpA patients already familiar with the use of the indices Testing was performed twice on two different days median interval 7 days range 4–10 days under standardised conditions in 26 outclinic patients median age 39 years range 22–56 years Limits of agreement were calculated as the 95 likely range for the difference between paired scores Test–retest results were significantly intercorrelated with r s = 090 for BASDAI 092 for BASFI and 074 for BASG Limits of agreement for BASDAI BASFI and BASG were ±18 ±14 and ±32 respectively Reproducibility as expressed as the mean of individual standard deviations was significantly poorer for BASG than for BASDAI and BASFI p 001 Internal consistency reliability and construct validity of BASDAI and BASFI were acceptable In conclusion in a sample of antiTNFtreated patients experienced with the use of BASDAI BASFI and BASG random measurement errors of the scores were not negligible The finding should be considered when monitoring antiTNF treatment in daily clinical practice
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