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Title of Journal: Clin Rheumatol

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Abbravation: Clinical Rheumatology

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Springer London

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DOI

10.1002/jez.1402190113

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1434-9949

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RAPID3 scores and hand outcome measurements in RA

Authors: Merita Qorolli Hajrije HundoziHysenaj Sylejman Rexhepi Blerta Rehxepi Simeon Grazio
Publish Date: 2016/12/28
Volume: 36, Issue: 6, Pages: 1379-1385
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Abstract

The Routine Assessment of Patient Index Data 3 RAPID3 is a patientreported disease activity measure used to assess physical function pain and global health in patients with rheumatoid arthritis RA without formal joint counts Since hand involvement and its decreased function are hallmarks of RA the aim of our study was to investigate the performance of RAPID3 scores with regard to hand function and to confirm previous findings that the RAPID3 score as a disease activity measure is strongly correlated with the DAS28 score Sixtyeight consecutive patients with RA 85 female aged 18–75 years were included in the study and were recruited during their outpatient visit Apart from demographic and clinical data the obtained parameters of interest included RAPID3 scores and assessments of the function of the hand namely the signal of functional impairment SOFIhand grip strength and pulptopalm distance as well the Health Assessment Questionnaire Disability Index HAQDI and DAS28 scores Pearson’s correlation coefficient Student’s t test and linear regression were used in the statistical analysis of the results The significance was set to p  005 A positive correlation was found between RAPID3 scores and HAQDI scores SOFIhand scores and pulptopalm distance and negative correlation was observed between RAPID3 scores and grip strength The order regarding the strength of correlations between RAPID3 scores and other variables from the strongest to the weakest was as follows HAQDI grip strength SOFIhand and pulptopalm distance The hand assessment variables had stronger correlations with RAPID3 scores than with DAS28 scores Our preliminary study showed that RAPID3 scores were strongly correlated with measurements of the functional ability of the hand demonstrating that RAPID3 can be used as a measure of disease activity in clinical practice and to characterize hand function Further studies are needed to confirm this result

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