Authors: Terhi M Uotila Jaakko A Antonen Antti S Paakkala Jukka T Mustonen Markku M Korpela for the Pirkanmaa Waterborne Outbreak Study Group
Publish Date: 2013/04/05
Volume: 32, Issue: 8, Pages: 1139-1145
Abstract
The purpose of the study was to assess the 1year outcome of definitive reactive arthritis ReA after a waterborne outbreak A cohort of 21 patients 15 females and 6 males median age 54 years with ReA related to an extensive waterborne outbreak in Finland was clinically followedup by rheumatologists with visits at baseline at 1 month and 3 6 and 12 months Although the outcome was in general favourable 1/3 of the patients had chronic course 7 33 of the 21 patients needed diseasemodifying antirheumatic drugs DMARDs and even 8 38 of them used glucocorticoids at 12 months Four 19 were using nonsteroidal antiinflammatory drugs and nine 43 other analgesics Many patients had articular pain and impaired physical function still at 12 months even though inflammatory parameters and the number of swollen joints were low Only one patient 5 was human leucocyte antigenB27positive She had the most severe ReA and also additional infectious arthritis caused by Salmonella serotype enteritidis leading to osteonecrosis of her hip joint with subsequent need for arthroplasty ReA as observed in our study was overall fairly mild but in many individuals postinfectious arthralgia and DMARD use continued at least up to 1 yearThe following investigators are members of the Pirkanmaa Waterborne Outbreak Study Group J Antonen P Collin J Helenius J Herrala T Katto M Korpela E Kujansuu AL Kuusela M Kuusi J Laine J Lumio S Mustajoki J Mustonen H Oksa P Ruutu S Räsänen and T Uotila This study was financially supported by the Competitive Research Funding of Tampere University Hospital Grants 9 L002 9 M124
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