Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Clin Rheumatol

Search In Journal Title:

Abbravation: Clinical Rheumatology

Search In Journal Abbravation:

Publisher

Springer-Verlag

Search In Publisher:

DOI

10.1007/978-3-642-28768-8_38

Search In DOI:

ISSN

1434-9949

Search In ISSN:
Search In Title Of Papers:

Detection of anticardiolipin antibody IgG by time

Authors: Yan Ye Zhigang Hu Jie Liu Guoqian Chen Yaohong Zhou Lei Yu
Publish Date: 2012/06/10
Volume: 31, Issue: 9, Pages: 1339-1345
PDF Link

Abstract

In an effort to improve the quantitative detection of anticardiolipin antibodies aCL IgG so as to classify patients correctly as antiphospholipid syndrome APS positive we developed a new immunoassay based on a sandwich timeresolved fluoroimmunoassay TRFIA using the complex of cardiolipin plus bovine β2GPI as antigen and Eu3+labeled rabbit antihuman IgG as conjugate The precision sensitivity specificity and stability of the assay were evaluated and comparison with the classical ELISA was also made The aCL IgG TRFIA kit we established had a wider detectable range than three commercial ELISA ones from different manufacturers when a specimen was diluted with strong positive result from 1125 to 1204800 The average intraassay and interassay CVs detected by the aCL IgG TRFIA was 314 and 370  respectively The sensitivity was 01 GPL U/ml and the clinical diagnostic specificity was 98  The established assay kit also behaved better in stability than the commercial ELISA ones Additionally the immunoassay we established correlated well with the ELISA and the correlation coefficient was 0975 We thus conclude that the TRFIA we developed for aCL IgG detection gives promise to a more sensitive and reliable diagnosis of APS and has potential value for largescale screening programs

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. A comparative study of arterial stiffness, flow-mediated vasodilation of the brachial artery, and the thickness of the carotid artery intima–media in patients with systemic autoimmune diseases
  2. The virtuoso foot
  3. Responsiveness of the DASH score in surgically treated basal joint arthritis of the thumb: preliminary results
  4. RAPID3 scores and hand outcome measurements in RA patients: a preliminary study
  5. Bone mineral density in children with familial Mediterranean fever
  6. Chorea as a side effect of gabapentin (Neurontin®) in a patient with complex regional pain syndrome Type 1
  7. Risk factors in transient osteoporosis: a retrospective study on 23 cases
  8. Outcome of reactive arthritis after an extensive Finnish waterborne gastroenteritis outbreak: a 1-year prospective follow-up study
  9. Elevated serum TRAIL levels in scleroderma patients and its possible association with pulmonary involvement
  10. The autonomic nervous system in systemic sclerosis. A review
  11. Prescription patterns and trends in anti-rheumatic drug use based on a large-scale claims database in Japan
  12. Rheumatoid arthritis: should we shift the focus from “Treat to Target” to “Treat to Work?”
  13. Intercellular adhesion molecules in systemic lupus erythematosus patients with lupus nephritis
  14. Severe deficiency of 25-hydroxyvitamin D 3 (25-OH-D 3 ) is associated with high disease activity of rheumatoid arthritis
  15. The expression of death decoy receptor 3 was increased in the patients with primary Sjögren’s syndrome
  16. Prognostic factors in a cohort of antisynthetase syndrome (ASS): serologic profile is associated with mortality in patients with interstitial lung disease (ILD)
  17. Tuberculosis infection in patients with systemic lupus erythematosus: pulmonary and extra-pulmonary infection compared
  18. Prolonged infections associated with antineutrophil cytoplasmic antibodies specific to proteinase 3 and myeloperoxidase: diagnostic and therapeutic challenge
  19. Group visits for rheumatoid arthritis patients: a pilot study
  20. Identification of transcription regulatory relationships in rheumatoid arthritis and osteoarthritis
  21. The impact of current health-related quality of life on future health outlook in patients with eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome)
  22. Two cases demonstrating thalidomide’s efficacy in refractory lupus nephritis
  23. Rheumatoid arthritis among Nigerians: the first 200 patients from a rheumatology clinic
  24. The challenge of profound hypoglycorrhachia: two cases of sarcoidosis and review of the literature
  25. Chronic intestinal pseudo-obstruction in patients with systemic lupus erythematosus: report of four cases
  26. Relationship of Q angle and joint hypermobility and Q angle values in different positions
  27. Osteoarthritis of the hip or knee: which coexisting disorders are disabling?
  28. Treatable renal disease in children with silent lupus nephritis detected by baseline biopsy: association with serum C3 levels
  29. T helper 1 type cytokines polymorphisms: association with susceptibility to Behçet’s disease
  30. Successful treatment of a patient with primary Sjögren's syndrome with Rituximab
  31. Oxidative status in rheumatoid arthritis
  32. Impact and therapy of osteoarthritis: the Arthritis Care OA Nation 2012 survey
  33. Follicular bronchiolitis, an unusual cause of haemoptysis in giant cell arteritis
  34. Treatment of acute neuropsychiatric lupus with intravenous immunoglobulin (IVIG): a case report and review of the literature
  35. Vitamin D and systemic lupus erythematosus: state of the art
  36. Challenges and opportunities for diagnosis and treatment of rheumatoid arthritis in Latin America
  37. Clostridium difficile : an under-recognized cause of reactive arthritis?
  38. Prevalence of rheumatic diseases in Raramuri people in Chihuahua, Mexico: a community-based study
  39. Clinical utility of magnetic resonance angiography (MRA) in the diagnosis and treatment of Takayasu’s arteritis
  40. A systematic review of homoeopathy for the treatment of fibromyalgia
  41. Do hip OA patients referred to orthopedic surgeons by general practitioners and rheumatologists differ?
  42. The pathway of estradiol-induced apoptosis in patients with systemic lupus erythematosus
  43. Antistreptococcal Response is Exaggerated in Children with Familial Mediterranean Fever
  44. High rate of disease remission in moderate rheumatoid arthritis on etanercept therapy: data from GISEA, the Italian biologics register
  45. Beware of the biologicals—hospitals may die: the Rheumatism Foundation Hospital, Heinola, Finland (1951–2010)
  46. Patterns of pain in Paget’s disease of bone and their outcomes on treatment with pamidronate
  47. QT dispersion in uncomplicated familial Mediterranean fever
  48. Ultrasonographic evaluation of the muscle architecture in patients with systemic lupus erythematosus
  49. Changes in mononuclear cell function in patients with rheumatoid arthritis following treatment with auranofin
  50. Risk of coronary artery disease in patients with systemic sclerosis: a systematic review and meta-analysis
  51. Autonomic dysfunction in psoriatic arthritis
  52. Exercise therapy for patients with diffuse idiopathic skeletal hyperostosis
  53. Reproducibility of the Bath Ankylosing Spondylitis Indices of disease activity (BASDAI), functional status (BASFI) and overall well-being (BAS-G) in anti-tumour necrosis factor-treated spondyloarthropathy patients
  54. The changes in monosaccharide composition of immunoglobulin G in the course of rheumatoid arthritis
  55. Increased expression of IL - 28RA mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
  56. Contrast-enhanced power Doppler sonography of knee synovitis in rheumatoid arthritis: assessment of therapeutic response
  57. Long-term follow-up of autologous stem cell transplantation for severe paediatric systemic lupus erythematosus
  58. Fibromyalgia and headache: an epidemiological study supporting migraine as part of the fibromyalgia syndrome
  59. Neridronate and human osteoblasts in normal, osteoporotic and osteoarthritic subjects
  60. Evaluation of a mail-delivered, print-format, self-management program for persons with systemic sclerosis
  61. Serum galectin-3 level in systemic sclerosis
  62. Non-rheumatoid erosive arthritis associated with type I hereditary angioedema
  63. Prevalence of soluble peptidylarginine deiminase 4 (PAD4) and anti-PAD4 antibodies in autoimmune diseases
  64. Familial Mediterranean fever responds well to infliximab: single case experience
  65. Prevalence of soluble peptidylarginine deiminase 4 (PAD4) and anti-PAD4 antibodies in autoimmune diseases
  66. The role of PET/CT in Cogan’s syndrome
  67. Treatment of osteoporosis in renal insufficiency
  68. STAT4 rs7574865 G/T polymorphism is associated with rheumatoid arthritis and disease activity, but not with anti-CCP antibody levels in a Mexican population
Search Result: