Authors: Ioannis M Varkarakis Germar Pinggera Nikolaos Antoniou Kostas Constantinides Michail Chrisofos Charalambos Deliveliotis
Publish Date: 2007/03/01
Volume: 39, Issue: 4, Pages: 1015-1021
Abstract
To evaluate cancer involvement of internal female genitalia of patients undergoing anterior exenteration for clinically organ confined transitional cell carcinoma of the bladder and identify potential preoperative risk factors Charts and anterior exenteration specimens from 54 women with clinically organ confined transitional cell bladder cancer were retrospectively reviewed Emphasis was given to the presence of internal genitalia involvement and or primary gynecologic pathology Unsuspected internal genitalia involvement was reported in only three patients 57 The vagina was involved in two cases 38 while the uterus in one 19 In all cases involvement was due to direst extension from bladder tumors of the base and dome respectively No preoperative variable could predict internal genitalia involvement in a statistical significant manner Benign pathology of the female reproductive organs was observed in six patients and involved in all cases the uterus 115 Internal genitalia involvement after radical cystectomy for TCC tumors of the bladder is rare 58 Preoperative risk factors could not be identified although all involved genitalia were seen in tumors of the bladder dome and base Therefore large multiinstitutional studies are needed in order to identify preoperative risk factors for internal genitalia involvement in females with bladder cancer
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