Authors: Istvan Mucsi Akos Ujszaszi Maria E Czira Marta Novak Miklos Z Molnar
Publish Date: 2013/08/20
Volume: 46, Issue: 3, Pages: 641-651
Abstract
Red cell distribution width RDW a parameter routinely reported as part of the complete blood count is associated with increased morbidity and mortality risk in different patient populations No published data are available about the association between RDW and mortality in kidney transplant recipientsWe collected sociodemographic clinical parameters medical and transplant history and laboratory data at baseline in 723 prevalent kidney transplant recipients between June and October 2008 mean age 51 ± 13 SD years 56 men 21 diabetics Associations between baseline RDW values and allcause mortality over 3 years were examined in unadjusted and adjusted modelsIncreasing RDW was associated with increased mortality in both unadjusted HR1 increase = 163 95 CI 141–189 and HRmedian = 274 95 CI 168–448 and fully adjusted models HR1 increase = 160 95 CI 127–189 and HRmedian = 133 95 CI 076–235 In reclassification analyses RDW improved the predictive value of allcause mortality prediction models the net reclassification improvement NRI was 0189 p 0001The authors thank the patients and the staff in the Department of Transplantation and Surgery Semmelweis University Budapest This study was supported by grants from the Hungarian Kidney Foundation Hungarian Society of Hypertension Hungarian Society of Nephrology and the Foundation for Prevention in Medicine MZ Molnar is recipient of the Hungarian Eötvös Scholarship MÖB/772/2012 A Ujszaszi is recipient of the Hungarian Eötvös Scholarship MÖB/773/2012
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