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Title of Journal: Int Urol Nephrol

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Abbravation: International Urology and Nephrology

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Springer Netherlands

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DOI

10.1007/s13762-013-0288-y

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ISSN

1573-2584

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Solifenacin objectively decreases urinary sensatio

Authors: Lior Lowenstein Kimberly Kenton Elizabeth R Mueller Linda Brubaker Edmond Sabo Ramón A DurazoArivzu Mary P FitzGerald
Publish Date: 2011/10/13
Volume: 44, Issue: 2, Pages: 425-429
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Abstract

To evaluate the test–retest reliability of a device that measures urinary sensation during cystometry and to use that device to determine whether treatment of overactive bladder syndrome OAB with solifenacin is associated with a change in urinary sensationOverall 15 women were recruited for this study ten women with OAB and urodynamically demonstrated detrusor overactivity and five controls without OAB underwent filling cystometry twice with contemporaneous continuous recording of urinary sensation Women with OAB received solifenacin 10 mg daily during the weeks between testing We compared the areas under the initial and repeat sensationvolume curvesWe present psychometric data demonstrating improved bladder sensation during the treatment of OAB with solifenacin If clinical correlations are confirmed by future study such urinary sensation measures may prove useful as assessment treatment predictor or outcome measures in OAB research and/or clinical care

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