Authors: Omer Necati Develioglu Sait Sirazi Murat Topak Sevim Purisa Mehmet Kulekci
Publish Date: 2012/11/22
Volume: 270, Issue: 5, Pages: 1655-1659
Abstract
This study aimed to evaluate the difference in mucociliary clearance among volunteers who underwent Ramadan versus Nineveh fasting regimens as well as the difference between the fasting period and 4 weeks following the fasting period in both groups In this study two different fasting groups were established Ramadan fasting for an average of 15 h for 29 consecutive days n = 40 and Nineveh 60 h of nonstop fasting n = 26 Subjects in each group underwent saccharin testing twice at the end of the fasting period prior to resumption of eating and at 4 weeks after the end of Ramadan or Nineveh fasting Statistical analysis was performed using the Mann–Whitney Utest Wilcoxon Chisquare and paired t test A p value less than 005 was considered statistically significant Forty subjects who underwent Ramadan fasting and 26 subjects who underwent Nineveh fasting were included in this study Of the 66 study participants 34 515 were men and 32 485 were women Their median age was 31 years range 17–70 years for Nineveh fasting subjects and 40 years range 17–70 years for Ramadan fasting subjects Chisquare tests revealed no significant difference between the Ramadan and Nineveh fasting groups in gender p = 0418 and the MannWhitney Utest showed no difference in age A statistically significant difference was found in the mucociliary clearance time between the Nineveh fasting and nonfasting periods p = 0013 Using Wilcoxon signedrank tests we found no significant difference in the mucociliary clearance time between the Ramadan fasting and control 4 weeks after the fasting period periods p = 0121 The percentage difference between the fasting and control periods was similar between groups and was not statistically significant for the Ramadan and Nineveh fasting groups p = 0086 The results of the present study indicated that longterm fasting with hypohydration contributed to the deterioration of nasal mucociliary clearance Our data indicate that optimal hydration sleep patterns and fasting times contribute to proper mucociliary clearance
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