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Title of Journal: Eur Arch Otorhinolaryngol

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Abbravation: European Archives of Oto-Rhino-Laryngology

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Springer Berlin Heidelberg

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DOI

10.1002/chin.201137244

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ISSN

1434-4726

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Diagnostic and prognostic value of procalcitonin l

Authors: Saffet Kilicaslan Sinan Uluyol Mehmet Hafit Gur Ilker Burak Arslan Ozlem Yagiz
Publish Date: 2016/02/19
Volume: 273, Issue: 6, Pages: 1615-1618
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Abstract

Inflammation is thought to play an important role in the pathogenesis of Bell’s palsy BP Procalcitonin PCT is currently among the most frequently used proinflammatory biomarkers in clinical practice In this study we assessed the serum PCT levels for predicting the severity and prognosis of BP In total 32 patients with House–Brackmann HB grade II and III BP lowgrade group 22 patients with HB grade IV and V highgrade group and 35 healthy individuals control group were included in this prospective study PCT levels were compared among these three groups at the time of diagnosis All patients received standard prednisolone and acyclovir treatment The correlation between PCT levels and recovery was analyzed 3 months after treatment The PCT levels for control lowgrade and highgrade BP groups were 001 ± 0001 035 ± 005 and 098 ± 041 ng/mL respectively The PCT level in lowgrade group was significantly higher than that in control group p  0001 and the PCT level in highgrade BP group was significantly higher than that in lowgrade group p = 001 p  005 The complete recovery rate was 937  in lowgrade and 545  in highgrade BP group p = 0015 p  005 There was a strong negative correlation between PCT levels and recovery rates r = −0896 p  0001 PCT levels were significantly associated with the severity of BP and higher PCT levels were related with poor clinical outcome in terms of recovery These results support the diagnostic and prognostic significance of PCT in patients with early BP

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