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Title of Journal: Eur Arch Otorhinolaryngol

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Abbravation: European Archives of Oto-Rhino-Laryngology

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Springer Berlin Heidelberg

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DOI

10.1007/bf03089897

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ISSN

1434-4726

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Relationship between the time to locoregional recu

Authors: Philippe Gorphe Yungan Tao Pierre Blanchard Caroline Even Antoine MoyaPlana Haïtham Mirghani France Nguyen Stéphane Temam François Janot
Publish Date: 2017/02/09
Volume: 274, Issue: 5, Pages: 2267-2271
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Abstract

To assess the relationship between the locoregional diseasefree interval after treatment of the primary tumor and survival after a recurrence in patients with laryngeal carcinoma We retrospectively investigated patients treated in our Cancer Center for a laryngeal cancer who subsequently developed a locoregional recurrence and were followed up until death Postrecurrence survival was defined as the time from the locoregional recurrence to death One hundred and twentythree patients were included Median postrecurrence survival was 7 months The locoregional diseasefree interval LRDFI after treatment of the primary was weakly correlated with postrecurrence survival r = 0210 p = 0020 A LRDFI cutoff of 12 months was a significant prognostic factor p = 0005 median 5 months 95 CI 2239–6761 vs 10 months 95 CI 7270–12730 The time to locoregional recurrence in laryngeal cancer was a prognostic factor correlated with postrecurrence survival Locoregional failure within the first year after treatment of the primary tumor was associated with an unfavorable prognosis

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