Authors: Nathalie Gabra MarcHenri Asmar Djamal Berbiche Issam Saliba
Publish Date: 2016/01/08
Volume: 273, Issue: 10, Pages: 2965-2973
Abstract
The aim of this study is to evaluate the quality of life QOL of patients treated by endolymphatic duct blockage EDB for Ménière’s disease with a dedicated questionnaire This is a retrospective crosssectional study which included 54 patients diagnosed with severe refractory Ménière’s disease according to the AAOHNS criteria and treated with EDB between 2010 and 2013 Answers to the first 38 questions have assigned scores from 0 to 4 0 corresponding to the poorest QOL A preoperative score called S1 was calculated as follows S1 = sum of preoperative question scores/maximum possible preoperative score ×100 The same formula was used to calculate the postoperative score S2 The change in QOL score S3 was then calculated S3 = S2−S1 All answers were analyzed anonymously Statistical analysis was done using Student t test and Chi square test A response rate of 89 was obtained with the Ménière’s disease outcome questionnaire The preoperative S1 score was 214 ±126 and the postoperative score S2 was 646 ±216 with a change in QOL S3 of 433 p 0001 Postoperatively 899 reported no Ménière’s attacks p 0001 Seventynine percent 15/19 of the questions showed a significant improvement after surgery These results show that EDB is associated with a significant improvement of the QOL of patients suffering from severe Ménière’s disease
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