Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: J Neural Transm

Search In Journal Title:

Abbravation: Journal of Neural Transmission

Search In Journal Abbravation:

Publisher

Springer-Verlag

Search In Publisher:

DOI

10.1007/bf00448361

Search In DOI:

ISSN

1435-1463

Search In ISSN:
Search In Title Of Papers:

Damage to oligodendrocytes in the striatum after M

Authors: S Takagi N Hayakawa H Kimoto H Kato T Araki
Publish Date: 2007/08/06
Volume: 114, Issue: 12, Pages: 1553-1557
PDF Link

Abstract

We investigated the alteration of oligodendrocytes in comparison with that of astrocytes and microglia in the mouse striatum after MPTP 1methyl4phenyl1236tetrahydropridine treatment under the same conditions using Western blot analysis and Immunohistochemistry In our Western blot analysis four administrations of MPTP at 2h intervals to mice produced the remarkable loss of TH tyrosine hydroxylase protein levels in the striatum after 3 and 7 days In contrast GFAP glial fibrillary acidic protein and Iba1 protein in the striatum showed a significant increase of GFAP and Iba1 protein levels 3 and 7 days after MPTP treatment On the other hand the levels of CNPase 2′ 3′cyclic nucleotide 3′phosphodiesterase protein were decreased significantly in the striatum 3 and 7 days after MPTP treatment In our immunohistochemical study a significant decrease in the area of expression of CNPasepositive profiles was observed in the striatum 3 and 7 days after MPTP treatment

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. A distinct variant of mixed dysarthria reflects parkinsonism and dystonia due to ephedrone abuse
  2. Effects of cholinesterase inhibitors on rat nicotinic receptor levels in vivo and in vitro
  3. Should magnesium be given to every migraineur? No
  4. CSF markers of neurodegeneration in Parkinson’s disease
  5. CSF markers of neurodegeneration in Parkinson’s disease
  6. Region-specific causal mechanism in the effects of ammonia on cerebral glucose metabolism in the rat brain
  7. The effects of buffer cations on interactions between mammalian copper-containing amine oxidases and their substrates
  8. Psychiatric disorders in adults diagnosed as children with atypical autism. A case control study
  9. Increase expression of α-synuclein in aged human brain associated with neuromelanin accumulation
  10. How does healthy aging impact on the circadian clock?
  11. Association between ACE polymorphism, cognitive phenotype and APOE E4 allele in a Tunisian population with Alzheimer disease
  12. TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer’s disease in Han Chinese
  13. Kynurenines in Parkinson’s disease: therapeutic perspectives
  14. Change in the expression of myelination/oligodendrocyte-related genes during puberty in the rat brain
  15. L-DOPA inhibits depolarization-induced [ 3 H]GABA release in the dopamine-denervated globus pallidus of the rat: the effect is dopamine independent and mediated by D2-like receptors
  16. Exercise inhibits neuronal apoptosis and improves cerebral function following rat traumatic brain injury
  17. The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach
  18. Does exposure to extremely low frequency magnetic fields produce functional changes in human brain?
  19. New insights into the structures and functions of human monoamine oxidases A and B
  20. DBS in Tourette syndrome: where are we standing now?
  21. Association between the RAGE G82S polymorphism and Alzheimer’s disease
  22. Differential modulation of alpha-1 adrenoceptor subtypes by antidepressants in the rat brain
  23. CSF and clinical hallmarks of subcortical dementias: focus on DLB and PDD
  24. Stimulation of D2 receptors in the prefrontal cortex reduces PCP-induced hyperactivity, acetylcholine release and dopamine metabolism in the nucleus accumbens
  25. Effects of extracellular pH reductions on [ 3 H] d -aspartate and [ 3 H]noradrenaline release by presynaptic nerve terminals isolated from rat cerebral cortex
  26. Circulating beta amyloid protein is elevated in patients with acute ischemic stroke
  27. Effects of dopaminergic replacement therapy on motor speech disorders in Parkinson’s disease: longitudinal follow-up study on previously untreated patients
  28. Both endogenous and exogenous ACh plays antinociceptive role in the hippocampus CA1 of rats
  29. Dopamine differently modulates central cholinergic circuits in patients with Alzheimer disease and CADASIL
  30. Nicotinic receptors and cognition in Parkinson’s Disease: the importance of neuronal synchrony
  31. Forty-two-years later: the outcome of childhood-onset schizophrenia
  32. Potential therapeutic system for Alzheimer’s disease: removal of blood Aβs by hemodialzyers and its effect on the cognitive functions of renal-failure patients
  33. Influence of diltiazem on the behavior of zolpidem-treated mice in the elevated-plus maze test
  34. The contribution of white matter lesions to Parkinson’s disease motor and gait symptoms: a critical review of the literature
  35. Facilitative effects of VNS on the motor threshold: implications for its antidepressive mode of action?
  36. Association between circadian rhythms, sleep and cognitive impairment in healthy older adults: an actigraphic study
  37. Mutation analysis of the seven in absentia homolog 1 (SIAH1) gene in Parkinson’s disease
  38. Mutation analysis of the seven in absentia homolog 1 (SIAH1) gene in Parkinson’s disease
  39. Time-dependent behavioral recovery after pneumococcal meningitis in rats
  40. Atrial fibrillation and stroke prevention: is warfarin still an option? Yes
  41. Editorial
  42. Bright light therapy in the treatment of childhood and adolescence depression, antepartum depression, and eating disorders
  43. Screening of two indel polymorphisms in the 5′UTR of the DJ - 1 gene in South African Parkinson’s disease patients
  44. Kainate receptor-mediated presynaptic inhibition converges with presynaptic inhibition mediated by Group II mGluRs and long-term depression at the hippocampal mossy fiber-CA3 synapse
  45. MR and GR functional SNPs may modulate tobacco smoking susceptibility
  46. The deep brain stimulation of the pedunculopontine tegmental nucleus: towards a new stereotactic neurosurgery
  47. Factors affecting the relative importance of amine oxidases and monooxygenases in the in vivo metabolism of xenobiotic amines in humans
Search Result: