Authors: María José GarcíaVelloso Matías Jurado Carolina Ceamanos José Manuel Aramendía María Puy Garrastachu Guillermo LópezGarcía José Ángel Richter
Publish Date: 2007/02/21
Volume: 34, Issue: 9, Pages: 1396-1405
Abstract
Eighty FDG PET scans were performed on 55 patients owing to suspicion of relapse and 45 FDG PET scans were performed on 31 patients who were clinically disease free PET results were compared with the results of conventional radiological imaging CIM and serum CA 125 levels and related to pathological findings in 54 cases or clinical followup in 71 casesCIM correctly identified 49 cases with recurrence sensitivity SE 533 and there were 27 true negatives specificity SP 818 However 43 cases were false negative and six were false positive The positive predictive value PPV negative predictive value NPV and accuracy ACC of CIM were 89 386 and 608 respectively FDG PET correctly detected recurrent disease in 80/92 cases SE 869 p 005 and ruled out relapse in 26/33 cases SP = 788 The PPV NPV and ACC of PET were 919 684 and 848 respectively Standardised uptake values did not provide additional diagnostic accuracy compared with visual analysis The CA 125 results showed an SE of 576 an SP of 939 and an ACC of 672 In 23 patients with positive serum CA 125 levels but negative CIM FDG PET was positive and relapse was confirmed Furthermore FDG PET was positive and relapse was confirmed in 11 patients with negative serum CA 125 levels and CIM
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