Authors: Abbas Güngördü Ayse Birhanli Murat Ozmen
Publish Date: 2012/07/17
Volume: 20, Issue: 1, Pages: 452-460
Abstract
The present study was undertaken to determine the toxic effect of a lethal concentration of six different commercially used textile dyes on the 46th stage of Xenopus laevis tadpoles The tadpoles were exposed to Astrazon Red FBL Astrazon Blue FGRL Remazol Red RR Remazol Turquoise Blue GA Cibacron Red FN3G and Cibacron Blue FNR for 168 h in static test conditions and thus 168h median lethal concentrations LC50s of each dye were determined to be 035 013 112 7 359 and 158 mg/L respectively Also to evaluate the sublethal effects of each dye tadpoles were exposed to different concentrations of dyes with respect to 168h LC50s for 24 h The alteration of selected enzyme activities was tested For this aim glutathione Stransferase GST carboxylesterase and lactate dehydrogenase LDH were assayed After dye exposure the GST induction or inhibition and LDH induction indicated some possible mechanisms of oxidative stress and deterioration in aerobic respiration processes induced by the tested dyes Findings of the study suggest that selected biomarker enzymes are useful in understanding the toxic mechanisms of these dyes in X laevis tadpoles as early warning indicators Therefore these selected biomarkers may evaluate the effect of environmental factors such as textile dye effluents and other industrial pollutants on amphibians in biomonitoring studies
Keywords: