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Title of Journal: Environ Sci Pollut Res

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Abbravation: Environmental Science and Pollution Research

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Springer Berlin Heidelberg

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DOI

10.1002/prac.18380140194

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1614-7499

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Fate of pharmaceutical compounds and steroid hormo

Authors: MarieVirginie Salvia Julie Experton Claire Geandel Cécile CrenOlivé Emmanuelle Vulliet
Publish Date: 2014/05/28
Volume: 21, Issue: 17, Pages: 10525-10535
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Abstract

Numerous chemical products are dispersed into the environment and the consequences can be sometimes harmful to humans and ecosystems Pharmaceutical compounds and hormone steroids are among these substances that concern the scientific community Currently little data are available on the presence and fate of these compounds in the environment and in particular for solid matrices Therefore the aim of this work was to perform soil column experiments to evaluate the accumulation transfer and degradation of these substances in soil The analyses were based on efficient sample preparation followed by sensitive and selective liquid chromatography coupled to tandem mass spectrometry LCMS/MS For this purpose 23 compounds were chosen including both pharmaceutical compounds as well as steroid hormones In addition this experiment was performed on two soils with different properties clay pH etc To the best of our knowledge no soil column experiments have been performed previously on a large number of pharmaceutical compounds and steroid hormones Significant transfer was observed only for sulphonamides that can be justified by their polarity log K ow   3 Furthermore some compounds have a cationic characteristic and are likely to be not much mobiles in soil due to cation exchange process However it was observed that the migration of the substances depends on the soil characteristics such as the amount of clay and the pH values Regarding the degradation it was noticed that substances degraded rapidly in the two soils Indeed for most substances their halflives were lower than 20 days Furthermore it was observed that the degradation rate depended on the soil


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