Authors: Petra Horka Karin Malickova Radka Jarosova Ivana Janatkova Tomas Zima Marta Kalousova
Publish Date: 2012/09/28
Volume: 29, Issue: 11, Pages: 1207-1212
Abstract
Sera and follicular fluids were obtained from 58 female patients treated for infertility by IVF Twentynine of them became pregnant after the embryotransfer another 29 were not successful in IVF and did not conceive Forty female nonpregnant blood donors and 38 healthy pregnant patients in the first trimester after the physiological conception were examined as control groups MMP2 and MMP9 were quantitively assessed using enzymelinked immunosorbent assayIVF females successfully conceiving after the IVF have shown the highest MMP9 concentrations in sera 8335 68609587 ng/mL and follicular fluids 96 60 170 ng/mL compared to all other examined cohorts Different behavior of MMP2 and MMP9 during the artificial ovulation was confirmed because only MMP9 has shown a vast difference between serum and follicular concentrations
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