Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: J Assist Reprod Genet

Search In Journal Title:

Abbravation: Journal of Assisted Reproduction and Genetics

Search In Journal Abbravation:

Publisher

Springer US

Search In Publisher:

DOI

10.1002/art.39632

Search In DOI:

ISSN

1573-7330

Search In ISSN:
Search In Title Of Papers:

Predictors of treatment failure in young patients

Authors: Marni B Jacobs Hillary KlonoffCohen Sanjay Agarwal Donna KritzSilverstein Suzanne Lindsay V Gabriel Garzo
Publish Date: 2016/05/06
Volume: 33, Issue: 8, Pages: 1001-1007
PDF Link

Abstract

Using deidentified clinic records 414 women 35 years undergoing their first autologous IVF cycle were identified Logistic regression was used to identify patientdriven clinical factors routinely collected during fertility treatment that could be used to model predicted probability of cycle failureOne hundred ninetyseven patients with both primary and secondary infertility had a failed IVF cycle and 217 with secondary infertility had a successful live birth None of the women with primary infertility had a successful live birth The significant predictors for IVF cycle failure among young patients were fewer previous live births history of biochemical pregnancies or spontaneous abortions lower baseline antral follicle count higher total gonadotropin dose unknown infertility diagnosis and lack of at least one fair to good quality embryo The full model showed good predictive value c = 0885 for estimating risk of cycle failure at ≥80  predicted probability of failure sensitivity = 554  specificity = 975  positive predictive value = 954  and negative predictive value = 698 All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards For this type of study formal consent is not required


Keywords:

References


.
Search In Abstract Of Papers:
Other Papers In This Journal:

  1. Time-lapse evaluation of human embryo development in single versus sequential culture media—a sibling oocyte study
  2. Clinical evaluation of two formulations of slow-freezing solutions for cleavage stage embryos
  3. Apoptotic sperm biomarkers and their correlation with conventional sperm parameters and male fertility potential
  4. Dehydroepiandrosterone (DHEA) supplementation results in supraphysiologic DHEA-S serum levels and progesterone assay interference that may impact clinical management in IVF
  5. CYP2C19 polymorphism increases the risk of endometriosis
  6. CYP2C19 polymorphism increases the risk of endometriosis
  7. Nuclei size in relation to nuclear status and aneuploidy rate for 13 chromosomes in donated four cells embryos
  8. The use of parthenotegenetic and IVF bovine blastocysts as a model for the creation of human embryonic stem cells under defined conditions
  9. Fifteen year follow-up of embryos cryopreserved in cancer patients for fertility preservation
  10. Live birth following transfer of a cryopreserved embryo generated from a cryopreserved oocyte and a cryopreserved sperm: Case report
  11. Use of the natural cycle and vitrification thawed blastocyst transfer results in better in-vitro fertilization outcomes
  12. Chromosome distribution of early miscarriages with present or absent embryos: female predominance
  13. Derivation of human embryonic stem cell lines from single blastomeres of low-quality embryos by direct plating
  14. Evaluation of in vitro fertilization parameters and estrogen receptor alpha gene polymorphisms for women with unexplained infertility
  15. Effect of the size of zona pellucida opening by laser assisted hatching on clinical outcome of frozen cleaved embryos that were cultured to blastocyst after thawing in women with multiple implantation failures of embryo transfer: a retrospective study
  16. IVF results in patients with very low serum AMH are significantly affected by chronological age
  17. Serum estradiol:oocyte ratio as a predictor of reproductive outcome: an analysis of data from >9000 IVF cycles in the Republic of Ireland
  18. Abnormally low expression of connexin 37 and connexin 43 in subcutaneously transplanted cryopreserved mouse ovarian tissue
  19. Association of WNT4 polymorphisms with endometriosis in infertile patients
  20. Day 3 ET, single blastocyst transfer (SBT) or frozen-thawed embryo transfer (FET): which is preferable for high responder patients in IVF/ICSI cycles?
  21. Sequential (hFSH + recFSH) vs homogenous (hFSH or recFSH alone) stimulation: clinical and biochemical (cumulus cell gene expression) aspects
  22. Correlation between follicular diameters and flushing versus no flushing on oocyte maturity, fertilization rate and embryo quality
  23. The role of epigenetics in idiopathic male infertility
  24. Deliveries of babies with normal health derived from oocytes with smooth endoplasmic reticulum clusters
  25. Dicer is a key player in oocyte maturation
  26. The vascular endothelial growth factor ( VEGF ) +405 G/C polymorphism and its relationship with recurrent implantation failure in women in an IVF programme with ICSI
  27. Clinically applied procedures for human ovarian tissue cryopreservation result in different levels of efficacy and efficiency
  28. Comparison of differences in development potentials between frozen-thawed D5 and D6 blastocysts and their relationship with pregnancy outcomes
  29. Luteal phase GnRHa trigger in random start fertility preservation cycles
  30. Feasibility and results of a modified intrafollicular insemination technique for treating primary infertility
  31. Caspase-3 and VEGF immunopositivity in seminiferous tubule germ cells in cases of obstructive and non-obstructive azoospermia in smokers versus non-smokers
  32. Relative expression of genes encoding SMAD signal transduction factors in human granulosa cells is correlated with oocyte quality
  33. Single nucleotide polymorphisms in the Anti-Müllerian hormone (AMH Ile 49 Ser) and Anti-Müllerian hormone type II receptor (AMHRII −482 A>G) as genetic markers in assisted reproduction technology
  34. Single thawed euploid embryo transfer improves IVF pregnancy, miscarriage, and multiple gestation outcomes and has similar implantation rates as egg donation
  35. Using the oocyte donation model to identify early trophoblast pregnenolone production
  36. Uterine vascularization and pregnancy outcome in patients undergoing intracytoplasmatic sperm injection: The role of nitric oxide
  37. Lack of carbon air filtration impacts early embryo development
  38. The importance of the cleavage stage morphology evaluation for blastocyst transfer in patients with good prognosis
  39. Improving fertilization rate in ICSI cycles by adding myoinositol to the semen preparation procedures: a prospective, bicentric, randomized trial on sibling oocytes
  40. Matrix metalloproteinases in serum and the follicular fluid of women treated by in vitro fertilization
  41. Bu Shen Tiao Chong recipe restores diminished ovary reserve through the BDNF pathway

Search Result: