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Title of Journal: Inflamm Bowel Dis

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Abbravation: Inflammatory Bowel Diseases

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Publisher

Narnia

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DOI

10.1002/zaac.200590011

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ISSN

1078-0998

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Microbial Causation of the Chronic Idiopathic Infl

Authors: Blaser Martin J
Publish Date: 1997/08/01
Volume: 3, Issue: 3, Pages: 225-229
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Abstract

The inability to find microbial causes for the idiopathic inflammatory bowel diseases has caused investigators and physicians to conclude that these IBDs are not infectious diseases However given the complexity of the intestinal flora and fauna and our very limited understanding of its microbiology it is quite possible that one or more etiologic agents for the IBDs exist but have not been detected Consideration of a number of models for how persistent microbes could cause disease as well as an analysis of the specific relationship of Helicobacter pylori to human disease facilitates new paradigms for analysis of the IBDs If the IBDs are due to microbial agents then the numerous immunological abnormalities observed are thus secondary phenomena The development of a more comprehensive knowledge base of the microbiology of the human intestine in general and of IBD patients in particular is most needed for advances to be made toward cure

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Other Papers In This Journal:
  1. Gender and Location of CRC in IBDImplications for Surveillance Protocols
  2. Protective effects of dietary curcumin in mouse model of chemically induced colitis are strain dependent
  3. Targeting TNF in Postoperative Recurrence of Crohn's Disease:Can We Extinguish the Fire Before It Starts?
  4. Gene Expression Profiling Identifies Mechanisms of Protection to Recurrent Trinitrobenzene Sulfonic Acid Colitis Mediated by Probiotics
  5. Adalimumab Therapy in Crohn's Disease of the Ileal Pouch
  6. Observations on Severity and Activity Indices in a Therapeutic Trial of Active Crohn's Disease
  7. Splenic function and IgM-memory B cells in Crohn's disease patients treated with infliximab
  8. One-year Investigator-blind Randomized Multicenter Trial Comparing Asacol 2.4 g Once Daily with 800 mg Three Times Daily for Maintenance of Remission in Ulcerative Colitis
  9. Role of diet in the development of inflammatory bowel disease
  10. Thromboembolism in pediatric inflammatory bowel disease: Systematic review
  11. Potential Oncogenic Properties of Mobilized Stem Cells in a Subpopulation of Inflammatory Bowel Disease Patients Infected with Helicobacter pylori
  12. Potential Oncogenic Properties of Mobilized Stem Cells in a Subpopulation of Inflammatory Bowel Disease Patients Infected with Helicobacter pylori
  13. Twin Studies Reveal Specific Imbalances in the Mucosaassociated Microbiota of Patients with Ileal Crohn's Disease
  14. Babesiosis in a Patient on Infliximab for Crohn's Disease
  15. Plasma Chromogranin A in Patients With Inflammatory Bowel Disease: A Possible Explanation
  16. Effect of Adalimumab on Clinical Laboratory Parameters in Patients with Crohn's Disease: Results from the CHARM Trial
  17. Natural history of bone metabolism and bone mineral density in children with inflammatory bowel disease
  18. What is the incidence, prevalence, and natural history of indeterminate colitis?
  19. Anti-tumor Necrosis Factor and Postoperative Complications in Crohn's Disease: Systematic Review and Meta-analysis
  20. Effects of T cell-induced colonic inflammation on epithelial barrier function†
  21. Seroreactivity to microbial components in Crohn's disease is associated with ileal involvement, noninflammatory disease behavior and NOD2/CARD15 genotype, but not with risk for surgery in a Hungarian cohort of IBD patients
  22. Multidrug resistance gene-1 polymorphisms and resistance to cyclosporine a in patients with steroid resistant ulcerative colitis
  23. Dangers associated with endoscopic management of strictures in IBD
  24. Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease†
  25. Role of the interleukin 24 in patients with ulcerative colitis
  26. Antibodies Against Cyclic Citrullinated Peptide (CCP) in Inflammatory Bowel Disease Patients With or Without Arthritic Manifestations
  27. Nitric Oxide and Colitis: Rats, Humans and Now Macaques
  28. Distinct Microbiome in Pouchitis Compared to Healthy Pouches in Ulcerative Colitis and Familial Adenomatous Polyposis
  29. Is Crohn's creeping fat an adipose tissue?
  30. Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease
  31. Cyclosporine in the management of severe ulcerative colitis while breast-feeding
  32. Nailing down the shingles in IBD
  33. Local Injection of Infliximab in Symptomatic Isolated Mucosal LesionsA Novel Scenario for Endoscopic Therapy?
  34. A New Type of Strictureplasty for the Treatment of Multiple Long Stenosis in Crohn's Disease
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